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Cancer is not (only) a senescence problem


Thomas, F and Vavre, F and Tissot, T and Vittecoq, M and Giraudeau, M and Bernex, F and Misse, D and Renaud, F and Raven, N and Beckmann, C and Hamede, R and Biro, PA and Ujvari, B, Cancer is not (only) a senescence problem, Trends in Cancer, 4, (3) pp. 169-172. ISSN 2405-8033 (2018) [Refereed Article]

Copyright Statement

Copyright 2018 Elsevier Ltd.

DOI: doi:10.1016/j.trecan.2018.01.002


Age is one of the strongest predictors of cancer and risk of death from cancer. Cancer is therefore generally viewed as a senescence-related malady. However, cancer also exists at subclinical levels in humans and other animals, but its earlier effects on the body are poorly known by comparison. We argue here that cancer is a significant but ignored burden on the body and is likely to be a strong selective force from early during the lifetime of an organism. It is time to adopt this novel view of malignant pathologies to improve our understanding of the ways in which oncogenic phenomena influence the ecology and evolution of animals long before their negative impacts become evident and fatal.

Item Details

Item Type:Refereed Article
Keywords:cancer, ecology, evolution
Research Division:Biological Sciences
Research Group:Evolutionary biology
Research Field:Host-parasite interactions
Objective Division:Environmental Management
Objective Group:Terrestrial systems and management
Objective Field:Control of pests, diseases and exotic species in terrestrial environments
UTAS Author:Hamede, R (Dr Rodrigo Hamede Ross)
ID Code:126018
Year Published:2018
Web of Science® Times Cited:13
Deposited By:Zoology
Deposited On:2018-05-18
Last Modified:2019-12-03

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