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Principles around accurate blood volume collection using capillary action

Citation

Lapierre, F and Gooley, A and Breadmore, M, Principles around accurate blood volume collection using capillary action, Langmuir, 33, (50) pp. 14220-14225. ISSN 0743-7463 (2017) [Refereed Article]


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DOI: doi:10.1021/acs.langmuir.7b02825

Abstract

Capillary action is one mechanism microfluidics uses to draw liquid autonomously in a substrate without the need of external energy. This behavior can be exploited to collect accurate volumes of liquids such as blood in narrow columns known as capillary tubes and help the development of inexpensive, user-friendly personalized biomedical tools. Precision bore glass capillaries demonstrate the "state of the art" for volume accuracy and precision, but height and radius must be carefully chosen in order to exploit the capillary action behavior efficiently. This Article investigates the influence of surface glass aging, due to prolonged exposure to humid air, and hematocrit level on the blood capillary rise. It provides also the tools to correctly define the optimum capillary dimensions to collect an accurate volume of blood in a glass capillary tube.

Item Details

Item Type:Refereed Article
Keywords:blood, capillary tubes, glass, microcirculation
Research Division:Chemical Sciences
Research Group:Analytical Chemistry
Research Field:Separation Science
Objective Division:Expanding Knowledge
Objective Group:Expanding Knowledge
Objective Field:Expanding Knowledge in the Chemical Sciences
Author:Lapierre, F (Dr Florian Lapierre)
Author:Gooley, A (Dr Andrew Gooley)
Author:Breadmore, M (Professor Michael Breadmore)
ID Code:125961
Year Published:2017
Deposited By:Austn Centre for Research in Separation Science
Deposited On:2018-05-17
Last Modified:2018-05-17
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