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The importance of synovial inflammation in osteoarthritis: current evidence from imaging assessments and clinical trials
Citation
Wang, X and Hunter, DJ and Jin, X and Ding, C, The importance of synovial inflammation in osteoarthritis: current evidence from imaging assessments and clinical trials, Osteoarthritis and Cartilage, 26, (2) pp. 165-174. ISSN 1063-4584 (2018) [Refereed Article]
Copyright Statement
© 2017 Osteoarthritis Research Society International. Published by Elsevier Ltd.
DOI: doi:10.1016/j.joca.2017.11.015
Abstract
Synovial abnormalities have been observed at multiple stages of osteoarthritis (OA). Increasing evidence suggests that it may play an important role in the OA pathological process. Many assessment systems using magnetic resonance imaging (MRI) and ultrasound have been established to detect synovial inflammation in OA. These have been used to inform the current investigation of OA disease phenotypes and progression and can be utilised in the future for clinical trials developing potential treatments. This narrative review aims to illustrate the importance of synovial tissue in OA and provide an overview of imaging assessments and possible therapies targeting synovial abnormalities.
Item Details
| Item Type: | Refereed Article |
|---|---|
| Keywords: | synovial inflammation, osteoarthritis, magnetic resonance imaging |
| Research Division: | Biomedical and Clinical Sciences |
| Research Group: | Clinical sciences |
| Research Field: | Rheumatology and arthritis |
| Objective Division: | Health |
| Objective Group: | Clinical health |
| Objective Field: | Clinical health not elsewhere classified |
| UTAS Author: | Ding, C (Professor Chang-Hai Ding) |
| ID Code: | 125729 |
| Year Published: | 2018 |
| Web of Science® Times Cited: | 65 |
| Deposited By: | Menzies Institute for Medical Research |
| Deposited On: | 2018-05-02 |
| Last Modified: | 2019-09-10 |
| Downloads: | 0 |
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