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The importance of synovial inflammation in osteoarthritis: current evidence from imaging assessments and clinical trials

Citation

Wang, X and Hunter, DJ and Jin, X and Ding, C, The importance of synovial inflammation in osteoarthritis: current evidence from imaging assessments and clinical trials, Osteoarthritis and Cartilage, 26, (2) pp. 165-174. ISSN 1063-4584 (2018) [Refereed Article]

Copyright Statement

2017 Osteoarthritis Research Society International. Published by Elsevier Ltd.

DOI: doi:10.1016/j.joca.2017.11.015

Abstract

Synovial abnormalities have been observed at multiple stages of osteoarthritis (OA). Increasing evidence suggests that it may play an important role in the OA pathological process. Many assessment systems using magnetic resonance imaging (MRI) and ultrasound have been established to detect synovial inflammation in OA. These have been used to inform the current investigation of OA disease phenotypes and progression and can be utilised in the future for clinical trials developing potential treatments. This narrative review aims to illustrate the importance of synovial tissue in OA and provide an overview of imaging assessments and possible therapies targeting synovial abnormalities.

Item Details

Item Type:Refereed Article
Keywords:synovial inflammation, osteoarthritis, magnetic resonance imaging
Research Division:Biomedical and Clinical Sciences
Research Group:Clinical sciences
Research Field:Rheumatology and arthritis
Objective Division:Health
Objective Group:Clinical health
Objective Field:Clinical health not elsewhere classified
UTAS Author:Ding, C (Professor Chang-Hai Ding)
ID Code:125729
Year Published:2018
Web of Science® Times Cited:42
Deposited By:Menzies Institute for Medical Research
Deposited On:2018-05-02
Last Modified:2019-09-10
Downloads:0

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