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We are now entering the very exciting era of treatment and management of diabetes mellitus (DM) with the emergence of new therapeutic agents, including sodium-glucose cotransporter 2 inhibitors (SGLT2i) and dipeptidyl peptidase-4 inhibitor (DPP-4i). From a cardiology and echocardiography perspective, the existence of diabetic cardiomyopathy has been proven through over four decades of discussion. DM is highly prevalent in patients with heart failure (HF). Independent associations are found after adjusting for hypertension (HTN) and coronary artery disease (CAD). In patients with both DM and HF, the prognosis is extremely dismal. In this review, the main focus is on both diabetic cardiomyopathy per se and its typical features (including myocardial additive insult related to DM), diagnosis, and management.

Item Type:	Refereed Article
Keywords:	diabetes mellitus (DM), diabetic cardiomyopathy, echocardiography, myocardial strain, sodium-glucose cotransporter 2 inhibitors (SGLT2i)
Research Division:	Biomedical and Clinical Sciences
Research Group:	Cardiovascular medicine and haematology
Research Field:	Cardiology (incl. cardiovascular diseases)
Objective Division:	Health
Objective Group:	Clinical health
Objective Field:	Clinical health not elsewhere classified
UTAS Author:	Negishi, K (Dr Kazuaki Negishi)
ID Code:	125456
Year Published:	2018
Web of Science® Times Cited:	16
Deposited By:	Menzies Institute for Medical Research
Deposited On:	2018-04-18
Last Modified:	2019-09-09
Downloads:	0