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Adherence to oral anticoagulants in atrial fibrillation: an Australian survey
Citation
Obamiro, KO and Chalmers, L and Lee, K and Bereznicki, BJ and Bereznicki, LR, Adherence to oral anticoagulants in atrial fibrillation: an Australian survey, Journal of Cardiovascular Pharmacology and Therapeutics, 23, (4) pp. 337-343. ISSN 1074-2484 (2018) [Refereed Article]
Copyright Statement
Copyright The Author(s) 2018
DOI: doi:10.1177/1074248418770201
Abstract
Background: The aim of this study was to investigate the proportion of patients who have suboptimal adherence to oral anticoagulant (OAC), identify the predictors of adherence, and determine whether patient-related factors vary across adherence levels in Australia.
Methods: Respondents were recruited for an online survey using Facebook. Survey instruments included the Morisky Medication Adherence Scale, the Anticoagulation Knowledge Tool, the Perception of Anticoagulant Treatment Questionnaires, and a modified Cancer Information Overload scale. Predictors of medication adherence were identified using ordinal regression analysis.
Results: Of the 386 responses eligible for analysis, only 54.9% reported a high level of adherence. Participants aged 65 years or younger were less likely to have high adherence compared to older participants (odds ratio [OR], 0.54; 95% confidence interval [CI], 0.33-0.88; P = .013), while females were more likely to be highly adherent compared to males (OR, 1.69; 95% CI, 1.08-2.64; P = .023). The analyses showed that age, gender, treatment satisfaction, information overload, concerns about making mistake when taking OACs, and cost of medication were significant predictors of adherence.
Conclusion: Self-reported suboptimal adherence to OAC is common among patients with atrial fibrillation. A focus on supporting people who are at higher risk of suboptimal adherence is needed to maximize the benefit of OAC therapy in this population.
Item Details
Item Type: | Refereed Article |
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Keywords: | adherence, oral anticoagulant, atrial fibrillation |
Research Division: | Biomedical and Clinical Sciences |
Research Group: | Pharmacology and pharmaceutical sciences |
Research Field: | Clinical pharmacy and pharmacy practice |
Objective Division: | Health |
Objective Group: | Other health |
Objective Field: | Other health not elsewhere classified |
UTAS Author: | Obamiro, KO (Dr Kehinde Obamiro) |
UTAS Author: | Chalmers, L (Dr Leanne Chalmers) |
UTAS Author: | Lee, K (Dr Kenneth Lee) |
UTAS Author: | Bereznicki, BJ (Dr Bonnie Bereznicki) |
UTAS Author: | Bereznicki, LR (Professor Luke Bereznicki) |
ID Code: | 125408 |
Year Published: | 2018 |
Web of Science® Times Cited: | 18 |
Deposited By: | Pharmacy |
Deposited On: | 2018-04-17 |
Last Modified: | 2019-03-25 |
Downloads: | 0 |
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