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The combination of exercise training and Zataria multiflora supplementation increase serum irisin levels in postmenopausal women


Ghanbari-Niaki, A and Saeidi, A and Ahmadian, M and Gharahcholo, L and Naghavi, N and Fazelzadeh, M and Mahjoub, S and Myers, S and Williams, A, The combination of exercise training and Zataria multiflora supplementation increase serum irisin levels in postmenopausal women, Integrative Medicine Research, 7, (1) pp. 44-52. ISSN 2213-4220 (2018) [Refereed Article]


Copyright Statement

Copyright 2018 Korea Institute of Oriental Medicine Licensed under Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0)

DOI: doi:10.1016/j.imr.2018.01.007


Background: We examined the effect of antioxidant supplementation and exercise on irisin within postmenopausal women.

Methods: Forty-eight participants (age: 55.7 4.9 years; weight: 68.0 6.3 kg; BMI 27.0 2.7; mean SD) were randomized into four groups for the eight week intervention: control group (CG; n = 12), resistance training group (RTG; n = 12), supplementation with Zataria multiflora group (ZG; n = 12), or supplementation with Z. multiflora and resistance training group (ZRTG; n = 12). RTG and ZRTG performed circuit resistance training, and both ZG and ZRTG consumed 500 mg of Z. multifloraevery day during the intervention. Blood samples were taken 48 hours before and after the intervention.

Results: There was a significant difference in irisin at post-training, with greater levels in ZRTG compared to CG. A significant increase was noted for irisin at post-training compared to pre-training for ZG, RTG, and ZRTG. Moreover, we identified a significant decrease in malondialdehyde in the RTG and ZRTG groups and increase in glutathione in the ZG, RTG, and ZRTG groups when compared to CG.

Conclusion: These findings showed that exercise, Z. multiflora supplementation or their combination led to an increase in irisin.

Item Details

Item Type:Refereed Article
Keywords:irisin, antioxidants, exericise, circuit resistance training, myokine, postmenopausal women, Zataria multiflora
Research Division:Biological Sciences
Research Group:Biochemistry and cell biology
Research Field:Cell metabolism
Objective Division:Health
Objective Group:Clinical health
Objective Field:Clinical health not elsewhere classified
UTAS Author:Myers, S (Dr Stephen Myers)
UTAS Author:Williams, A (Associate Professor Andrew Williams)
ID Code:124892
Year Published:2018
Web of Science® Times Cited:15
Deposited By:Health Sciences
Deposited On:2018-03-16
Last Modified:2022-08-19
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