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Polygodial: a viable natural product scaffold for the rapid synthesis of novel polycyclic pyrrole and pyrrolidine derivatives
journal contribution
posted on 2023-05-19, 16:37 authored by Rihak, KJ, Alexander BissemberAlexander Bissember, Jason SmithJason SmithThe dialdehyde polygodial was utilised as a chiral scaffold for the unified synthesis of novel polycyclic pyrrole and pyrrolidine derivatives. Mechanistic insight into the reaction of primary amines with this dialdehyde was obtained. In addition, one of these polycyclic pyrroles was transformed further to prepare novel pentacyclic frameworks.
History
Publication title
TetrahedronVolume
74Issue
12Pagination
1167-1174ISSN
0040-4020Department/School
School of Natural SciencesPublisher
Pergamon-Elsevier Science LtdPlace of publication
The Boulevard, Langford Lane, Kidlington, Oxford, England, Ox5 1GbRights statement
Copyright 2017 Elsevier Ltd.Repository Status
- Restricted