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Methods for the synthesis of annulated pyrroles via cyclisation strategies


Olivier, WJ and Smith, JA and Bissember, AC, Methods for the synthesis of annulated pyrroles via cyclisation strategies, Organic and Biomolecular Chemistry, 16, (8) pp. 1216-1226. ISSN 1477-0520 (2018) [Refereed Article]

Copyright Statement

© The Royal Society of Chemistry 2018

DOI: doi:10.1039/C7OB03144K


Pyrrole, pyrrolidine, and indolizidine alkaloids represent important classes of natural products. Historically, these heterocycles and their derivatives have been the focus of significant interest in organic synthesis. In this report, we review the methods that have been employed to synthesise annulated pyrroles via transformations that include: Friedel–Crafts acylations and alkylations, Michael additions, Heck couplings, hydroarylations, carbenoid insertions, and radical cyclisations.

Item Details

Item Type:Refereed Article
Keywords:pyrrole, organic synthesis, methodology, heterocyclic chemistry
Research Division:Chemical Sciences
Research Group:Organic chemistry
Research Field:Organic chemical synthesis
Objective Division:Expanding Knowledge
Objective Group:Expanding knowledge
Objective Field:Expanding knowledge in the chemical sciences
UTAS Author:Olivier, WJ (Mr Wesley Olivier)
UTAS Author:Smith, JA (Associate Professor Jason Smith)
UTAS Author:Bissember, AC (Associate Professor Alex Bissember)
ID Code:124510
Year Published:2018
Web of Science® Times Cited:38
Deposited By:Chemistry
Deposited On:2018-02-23
Last Modified:2022-08-18

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