eCite Digital Repository

Anticoagulation knowledge in patients with atrial fibrillation: an Australian survey


Obamiro, KO and Chalmers, L and Lee, K and Bereznicki, BJ and Bereznicki, LRE, Anticoagulation knowledge in patients with atrial fibrillation: an Australian survey, International journal of clinical practice, 72, (3) Article e13072. ISSN 1368-5031 (2018) [Refereed Article]

Copyright Statement

Copyright 2018 John Wiley & Sons Ltd

DOI: doi:10.1111/ijcp.13072


Background: Atrial fibrillation (AF) is the most commonly diagnosed arrhythmia in clinical practice, and is associated with a significant medical and economic burden. Anticoagulants reduce the risk of stroke and systemic embolism by approximately two-thirds compared with no therapy. Knowledge regarding anticoagulant therapy can influence treatment outcomes in patients with AF.

Objective: To measure the level of anticoagulation knowledge in patients with AF taking oral anticoagulants (OACs), investigate the association between patient-related factors and anticoagulation knowledge, and compare these results in patients taking warfarin and direct-acting oral anticoagulant (DOACs).

Methods: Participants were recruited for an online survey via Facebook. Survey components included the Anticoagulation Knowledge Tool, the Perception of Anticoagulant Treatment Questionnaires (assessing treatment expectations, convenience and satisfaction), a modified Cancer Information Overload scale and the Morisky Medication Adherence Scale. Treatment groups were compared and predictors of OAC knowledge were identified.

Results: Participants taking warfarin had a higher knowledge score compared with those taking DOACs (n = 386, 73% 13% vs 66% 14%, P<.001). Advancing age, type of OAC, health information overload and ease of OAC use (treatment expectation) were significant predictors of knowledge. Treatment expectation, including the belief that OAC treatment would cause bleeding side effects, varied significantly between participants taking warfarin and DOACs (P = .011).

Conclusion: The study identified knowledge gaps in patients taking OACs, and these deficiencies appeared to be greater in participants taking DOACs. Knowledge assessment should be integrated into patient counselling sessions to help identify and resolve knowledge deficits.

Item Details

Item Type:Refereed Article
Keywords:adherence, knowledge, anticoagulation
Research Division:Biomedical and Clinical Sciences
Research Group:Pharmacology and pharmaceutical sciences
Research Field:Clinical pharmacy and pharmacy practice
Objective Division:Health
Objective Group:Other health
Objective Field:Other health not elsewhere classified
UTAS Author:Obamiro, KO (Dr Kehinde Obamiro)
UTAS Author:Chalmers, L (Dr Leanne Chalmers)
UTAS Author:Lee, K (Dr Kenneth Lee)
UTAS Author:Bereznicki, BJ (Dr Bonnie Bereznicki)
UTAS Author:Bereznicki, LRE (Professor Luke Bereznicki)
ID Code:124381
Year Published:2018
Web of Science® Times Cited:20
Deposited By:Pharmacy
Deposited On:2018-02-20
Last Modified:2019-02-22

Repository Staff Only: item control page