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Molecular evidence of Chlamydia pecorum and arthropod-associated Chlamydiae in an expanded range of marsupials

Citation

Burnard, D and Huston, WM and Webb, JK and Jelocnik, M and Reiss, A and Gillett, A and Fitzgibbon, S and Carver, S and Carrucan, J and Flanagan, C and Timms, P and Polkinghorne, A, Molecular evidence of Chlamydia pecorum and arthropod-associated Chlamydiae in an expanded range of marsupials, PLoS One, 7, (1) Article 12844. ISSN 1932-6203 (2017) [Refereed Article]


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Copyright 2017 The Authors. Licensed under Creative Commons Attribution 4.0 International (CC BY 4.0) https://creativecommons.org/licenses/by/4.0/

DOI: doi:10.1038/s41598-017-13164-y

Abstract

The order Chlamydiales are biphasic intracellular bacterial pathogens infecting humans and domesticated animals. Wildlife infections have also been reported, with the most studied example being Chlamydia pecorum infections in the koala, an iconic Australian marsupial. In koalas, molecular evidence suggests that spill-over from C. pecorum infected livestock imported into Australia may have had a historical or contemporary role. Despite preliminary evidence that other native Australian marsupials also carry C. pecorum, their potential as reservoirs of this pathogen and other Chlamydia-related bacteria (CRBs) has been understudied. Mucosal epithelial samples collected from over 200 native Australian marsupials of different species and geographic regions across Australia were PCR screened for Chlamydiales. Previously described and genetically distinct C. pecorum genotypes and a range of 16S rRNA genotypes sharing similarity to different CRBs in the broader Chlamydiales order were present. One 16S rRNA Chlamydiales genotype recently described in Australian ticks that parasitise native Australian marsupials was also identified. This study provides further evidence that chlamydial infections are widespread in native fauna and that detailed investigations are required to understand the influence these infections have on host species conservation, but also whether infection spill-over plays a role in their epidemiology.

Item Details

Item Type:Refereed Article
Keywords:Chlamydia, possum, koala, marsupial, wildlife infection
Research Division:Agricultural and Veterinary Sciences
Research Group:Veterinary Sciences
Research Field:Veterinary Microbiology (excl. Virology)
Objective Division:Health
Objective Group:Public Health (excl. Specific Population Health)
Objective Field:Disease Distribution and Transmission (incl. Surveillance and Response)
Author:Carver, S (Dr Scott Carver)
ID Code:124335
Year Published:2017
Funding Support:Australian Research Council (LP140100315)
Web of Science® Times Cited:1
Deposited By:Zoology
Deposited On:2018-02-19
Last Modified:2018-05-09
Downloads:6 View Download Statistics

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