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Gold-catalyzed domino cyclization-alkynylation reactions with EBX reagents: new insights into the reaction mechanism

Citation

Ghari, H and Li, Y and Roohzadeh, R and Caramenti, P and Waser, J and Ariafard, A, Gold-catalyzed domino cyclization-alkynylation reactions with EBX reagents: new insights into the reaction mechanism, Dalton Transactions, 46, (36) pp. 12257-12262. ISSN 1477-9226 (2017) [Refereed Article]


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DOI: doi:10.1039/c7dt03154h

Abstract

Gold-catalyzed domino processes constitute a useful alternative to CH functionalization for the synthesis of functionalized (hetero)arenes. Herein, we report computational studies on the gold-catalyzed cyclization alkynylation of keto-allenes with ethynylbenziodoxole (EBX) reagents, which identified a gold(I) picolinate complex as the active catalyst, giving the first mechanistic insights into this transformation.

Item Details

Item Type:Refereed Article
Keywords:catalysis, gold, CH functionalization, DFT calculation, hypervalent iodine
Research Division:Chemical Sciences
Research Group:Physical Chemistry (incl. Structural)
Research Field:Catalysis and Mechanisms of Reactions
Objective Division:Expanding Knowledge
Objective Group:Expanding Knowledge
Objective Field:Expanding Knowledge in the Chemical Sciences
Author:Ariafard, A (Associate Professor Alireza Ariafard)
ID Code:123465
Year Published:2017
Web of Science® Times Cited:1
Deposited By:Chemistry
Deposited On:2018-01-09
Last Modified:2018-01-09
Downloads:0

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