Buscot, M-J and Thomson, RJ and Juonala, M and Sabin, MA and Burgner, DP and Lehtimaki, T and Hutri-Kahonen, N and Viikari, JSA and Jokinen, E and Tossavainen, P and Laitinen, T and Raitakari, OT and Magnussen, CG, BMI trajectories associated with resolution of elevated youth BMI and incident adult obesity, Pediatrics, 141, (1) Article e20172003. ISSN 0031-4005 (2018) [Refereed Article]
Copyright 2018 by the American Academy of Pediatrics
Methods: Bayesian hierarchical piecewise regression modeling was used to analyze the BMI trajectories of 2717 young adults who had up to 8 measures of BMI from childhood (ages 3-18 years) to adulthood (ages 34-49 years).
Results: Compared with those with persistently high BMI, those who resolved their high youth BMI by adulthood had lower average BMI at age 6 years and slower rates of BMI change from young childhood. In addition, their BMI levels started to plateau at 16 years old for females and 21 years old for males, whereas the BMI of those whose high BMI persisted did not stabilize until 25 years old for male subjects and 27 years for female subjects. Compared with those youth who were not overweight or obese and who remained nonobese in adulthood, those who developed obesity had a higher BMI rate of change from 6 years old, and their BMI continued to increase linearly until age 30 years.
Conclusions: Efforts to alter BMI trajectories for adult obesity should ideally commence before age 6 years. The natural resolution of high BMI starts in adolescence for males and early adulthood for females, suggesting a critical window for secondary prevention.
|Item Type:||Refereed Article|
|Keywords:||body mass index, trajectories, child, adult, obesity|
|Research Division:||Health Sciences|
|Research Field:||Epidemiology not elsewhere classified|
|Objective Group:||Clinical health|
|Objective Field:||Clinical health not elsewhere classified|
|UTAS Author:||Buscot, M-J (Dr Marie-Jeanne Buscot)|
|UTAS Author:||Magnussen, CG (Associate Professor Costan Magnussen)|
|Funding Support:||National Health and Medical Research Council (1098369)|
|Web of Science® Times Cited:||38|
|Deposited By:||Menzies Institute for Medical Research|
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