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Amperometric detection of organic thiols at a tungsten wire electrode following their separation by liquid chromatography

Citation

Hidayat, A and Hibbert, DB and Alexander, PW, Amperometric detection of organic thiols at a tungsten wire electrode following their separation by liquid chromatography, Journal of Chromatography B, 693, (1) pp. 139-146. ISSN 0378-4347 (1997) [Refereed Article]

DOI: doi:10.1016/S0378-4347(97)00054-6

Abstract

The amperometric detection of thiols following their separation by reversed-phase chromatography and reaction into a post-column mercury carrier stream is shown to be a sensitive method when using a tungsten wire sensor as the working electrode in a three-electrode flow cell. Five organic thiols (cysteine, homocysteine, reduced glutathione, D,L-penicillamine and 2-mercaptopropionic acid) and thiourea could be separated within approx. 18 min. The analytical performance is comparable, and stability superior, to chemically modified electrodes previously reported.

Item Details

Item Type:Refereed Article
Research Division:Chemical Sciences
Research Group:Analytical Chemistry
Research Field:Instrumental Methods (excl. Immunological and Bioassay Methods)
Objective Division:Expanding Knowledge
Objective Group:Expanding Knowledge
Objective Field:Expanding Knowledge in the Chemical Sciences
Author:Alexander, PW (Professor Peter Alexander)
ID Code:12262
Year Published:1997
Web of Science® Times Cited:23
Deposited By:Applied Science
Deposited On:1997-08-01
Last Modified:2011-08-15
Downloads:0

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