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Considerations for treatment, diagnosis and risk factors for critical care polyneuropathy


McKittrick, A and Kornhaber, RA and Visentin, DC and Cleary, M and Haik, J and Harats, M, Considerations for treatment, diagnosis and risk factors for critical care polyneuropathy, 41st Annual Scientific Meeting (ASM), of the Australian & New Zealand Burn Association (ANZBA), 24-27 October 2017, Adelaide (2017) [Conference Extract]

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Background: Critical care polyneuropathy is a neuromuscular weakness that may be experienced in severe burn patients managed in intensive care with prolonged ventilation (Chan, Ng & Vandervord, 2010). Reducing long-term functional impairment requires early diagnosis. However, early diagnosis remains difficult with varying levels of sedation.

Aim: To identify the precipitating factors that contribute to the development of critical care polyneuropathy in severe burn injury.

Methods: An integrative review was undertaken, using a systematic approach. Research papers and case reports from the international literature were included in the review.

Results: The research studies identified an incidence of critical care polyneuropathy of 4.4% amongst a surveyed population comprising 2755 burns patients with a mean total burn surface area of 40%. While the risk factors have been poorly reported across the studies, the survey identified prolonged ventilation, failure to wean from a ventilator, larger and deeper burns and the occurrence of sepsis as causative factors.

Conclusion: Early identification of critical care polyneuropathy and subsequent intensive therapy is an important aspect in patientsí recovery that may strengthen activity and exercise tolerance. The long-term impact of critical care neuropathy therefore warrants further longitudinal investigation, and this review highlights the need for more systematic measurement and reporting of risk factors and assessment.

Item Details

Item Type:Conference Extract
Keywords:critical are neuropathy
Research Division:Biomedical and Clinical Sciences
Research Group:Neurosciences
Research Field:Peripheral nervous system
Objective Division:Health
Objective Group:Provision of health and support services
Objective Field:Allied health therapies (excl. mental health services)
UTAS Author:Kornhaber, RA (Dr Rachel Kornhaber)
UTAS Author:Visentin, DC (Dr Denis Visentin)
UTAS Author:Cleary, M (Professor Michelle Cleary)
ID Code:122068
Year Published:2017
Deposited By:Health Sciences
Deposited On:2017-10-30
Last Modified:2017-11-27

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