eCite Digital Repository
Association of the active and passive components of left atrial deformation with left ventricular function
Citation
Ramkumar, S and Yang, H and Wang, Y and Nolan, M and Negishi, T and Negishi, K and Marwick, TH, Association of the active and passive components of left atrial deformation with left ventricular function, Journal of the American Society of Echocardiography, 30, (7) pp. 659-666. ISSN 0894-7317 (2017) [Refereed Article]
Copyright Statement
Copyright 2017 by the American Society of Echocardiography.
DOI: doi:10.1016/j.echo.2017.03.014
Abstract
Methods: Echocardiography was undertaken in a community-based study of 576 participants ≥ 65 years of age with one or more risk factors (e.g., hypertension, diabetes mellitus, obesity). Strain analysis was conducted using a dedicated software package, using R-R gating. LV function was classified as normal in the presence of global longitudinal strain (GLS) (≤ -18%) or global circumferential strain (GCS) (≤ -22%). The associations between GLS or GCS and LA reservoir, conduit, and pump strain were assessed using univariate and multivariate linear regression.
Results: Patients (mean age 71 ± 5 years, 54% women) with reduced GLS had higher blood pressure and rates of diabetes and obesity (P < .05). LA reservoir strain and conduit strain were lower in the group with impaired GLS (38.2 ± 7.3% vs 39.9 ± 6.4% [P = .004] and 18.7 ± 5.7% vs 20.5 ± 5.1% [P < .001], respectively), but there was no difference in LA pump strain (19.5 ± 5.5% vs 19.3 ± 4.6%, P = .72). GLS was independently associated with LA reservoir and conduit strain (P < .05) but not independently associated with LA pump strain (P = .91). Reduced GCS was associated with a larger body mass index, male sex, and diabetes (P < .05). There were no differences in LA reservoir, conduit, and pump strain in patients with normal and abnormal GCS (P > .05).
Conclusions: The application of LA strain is specific to the component measured. LA pump strain is independent of LV mechanics.
Item Details
Item Type: | Refereed Article |
---|---|
Keywords: | atrial function, left atrium, left ventricle, strain |
Research Division: | Biomedical and Clinical Sciences |
Research Group: | Cardiovascular medicine and haematology |
Research Field: | Cardiology (incl. cardiovascular diseases) |
Objective Division: | Health |
Objective Group: | Clinical health |
Objective Field: | Clinical health not elsewhere classified |
UTAS Author: | Yang, H (Ms Hilda Yang) |
UTAS Author: | Wang, Y (Ms Ying Wang) |
UTAS Author: | Nolan, M (Mr Mark Nolan) |
UTAS Author: | Negishi, T (Dr Tomoko Negishi) |
UTAS Author: | Negishi, K (Dr Kazuaki Negishi) |
UTAS Author: | Marwick, TH (Professor Tom Marwick) |
ID Code: | 121389 |
Year Published: | 2017 |
Web of Science® Times Cited: | 27 |
Deposited By: | Menzies Institute for Medical Research |
Deposited On: | 2017-09-27 |
Last Modified: | 2018-06-22 |
Downloads: | 0 |
Repository Staff Only: item control page