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Interplay of the quality of ciprofloxacin and antibiotic resistance in developing countries
Citation
Sharma, D and Patel, RP and Zaidi, STR and Sarker, MMR and Lean, QY and Ming, LC, Interplay of the quality of ciprofloxacin and antibiotic resistance in developing countries, Frontiers in Pharmacology, 8 Article 546. ISSN 1663-9812 (2017) [Refereed Article]
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Copyright Statement
Copyright 2017 The Author(s) Licensed under Creative Commons Attribution 4.0 International (CC BY 4.0) https://creativecommons.org/licenses/by/4.0/
DOI: doi:10.3389/fphar.2017.00546
Abstract
Ciprofloxacin, a second generation broad spectrum fluoroquinolone, is active against both Gram-positive and Gram-negative bacteria. Ciprofloxacin has a high oral bioavailability and a large volume of distribution. It is used for the treatment of a wide range of infections including urinary tract infections caused by susceptible bacteria. However, the availability and use of substandard and spurious quality of oral ciprofloxacin formulations in the developing countries has been thought to have contributed toward increased risk of treatment failure and bacterial resistance. Therefore, quality control and bioequivalence studies of the commercially available oral ciprofloxacin formulations should be monitored. Appropriate actions should be taken against offending manufacturers in order to prevent the sale of substandard and spurious quality of ciprofloxacin formulations.
Item Details
| Item Type: | Refereed Article |
|---|---|
| Keywords: | antimicrobials, antibiotic resistance, ciprofloxacin, quality assurance, substandard drug, spurious drug, pharmacovigilence and drug monitoring, drug regulatory system, fluoroquinolones |
| Research Division: | Medical and Health Sciences |
| Research Group: | Pharmacology and Pharmaceutical Sciences |
| Research Field: | Clinical Pharmacology and Therapeutics |
| Objective Division: | Health |
| Objective Group: | Clinical Health (Organs, Diseases and Abnormal Conditions) |
| Objective Field: | Infectious Diseases |
| UTAS Author: | Sharma, D (Mrs Deepali Sharma) |
| UTAS Author: | Patel, RP (Dr Rahul Patel) |
| UTAS Author: | Zaidi, STR (Dr Tabish Razi Zaidi) |
| UTAS Author: | Ming, LC (Dr Long Ming) |
| ID Code: | 120462 |
| Year Published: | 2017 |
| Web of Science® Times Cited: | 10 |
| Deposited By: | Pharmacy |
| Deposited On: | 2017-08-25 |
| Last Modified: | 2018-12-13 |
| Downloads: | 113 View Download Statistics |
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