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Electrophoretic separations on paper: past, present, and future - a review
journal contribution
posted on 2023-05-22, 23:49 authored by Pavisara Nanthasurasak, Cabot, JM, See, HH, Rosanne Guijt, Michael BreadmoreMichael BreadmorePoint-of-collection (POC) devices aim for a fast, on-site detection for medical and environmental purposes. In this area, microfluidic Paper-based Analytical Devices (μPADs) have recently gained popularity because these are potentially cheap and environmentally friendly to produce, and easy to use. From an analytical perspective, paper is well known for its use as a substrate for chromatography, but less known for its use in electrophoretic separations. With the recent interest in μPADs, most applications are based on rather simple assays with relatively few applications incorporating an analytical separation. The focus of this review is on paper-based electrophoresis, originating with the key developments in the 1940s and 1950s as well as the recent developments of electrophoretic μPADs, and concluding with a critical discussion of the opportunities and challenges for electrophoretic μPADS in the future.
History
Publication title
Analytica Chimica ActaVolume
685Pagination
7-23ISSN
0003-2670Department/School
School of Natural SciencesPublisher
Elsevier Science BvPlace of publication
Po Box 211, Amsterdam, Netherlands, 1000 AeRepository Status
- Restricted