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Quinine-induced severe thrombocytopenia: the importance of taking a detailed drug history
journal contribution
posted on 2023-05-19, 09:03 authored by Muhajir MohamedMuhajir Mohamed, Hayes, RDrugs can lead to severe life-threatening thrombocytopenia. The mechanisms of drug-induced thrombocytopenia are increased destruction by immunemediated platelet destruction or decreased platelet production by bone marrow suppression. Quinine is a drug used for the treatment of malaria and nocturnal leg cramps and is also an important ingredient in some herbal preparations. Quinine can very rarely cause thrombocytopenia by immune-mediated platelet destruction. In a patient with thrombocytopenia, a detailed history of all the medications including over-the-counter medications and herbal preparations is very important.
History
Publication title
BMJ Case ReportsVolume
2013Issue
3 October 2013Article number
200631Number
200631Pagination
1-3ISSN
1757-790XDepartment/School
Tasmanian School of MedicinePublisher
BMJ GroupPlace of publication
United KingdomRights statement
Copyright 2013 BMJ Publishing GroupRepository Status
- Restricted