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Quinine-induced severe thrombocytopenia: the importance of taking a detailed drug history

journal contribution
posted on 2023-05-19, 09:03 authored by Muhajir MohamedMuhajir Mohamed, Hayes, R
Drugs can lead to severe life-threatening thrombocytopenia. The mechanisms of drug-induced thrombocytopenia are increased destruction by immunemediated platelet destruction or decreased platelet production by bone marrow suppression. Quinine is a drug used for the treatment of malaria and nocturnal leg cramps and is also an important ingredient in some herbal preparations. Quinine can very rarely cause thrombocytopenia by immune-mediated platelet destruction. In a patient with thrombocytopenia, a detailed history of all the medications including over-the-counter medications and herbal preparations is very important.

History

Publication title

BMJ Case Reports

Volume

2013

Issue

3 October 2013

Article number

200631

Number

200631

Pagination

1-3

ISSN

1757-790X

Department/School

Tasmanian School of Medicine

Publisher

BMJ Group

Place of publication

United Kingdom

Rights statement

Copyright 2013 BMJ Publishing Group

Repository Status

  • Restricted

Socio-economic Objectives

Diagnosis of human diseases and conditions

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