Bittinger, SE and Nazaretian, SP and Gook, DA and Parmar, C and Harrup, R and Stern, CJ, Detection of Hodgkin lymphoma within ovarian tissue, Fertility and Sterility, 95, (2) pp. 803.e3-803.e6. ISSN 0015-0282 (2011) [Refereed Article]
Design: Case report. Setting: University-affiliated women's hospital. Patient(s): A 19-year-old woman diagnosed with Hodgkin lymphoma. Intervention(s): Laparoscopic removal of ovarian tissue for cryopreservation.
Main Outcome Measure(s): Histologic and immunohistochemical evaluation of ovarian tissue harvested for fertility preservation.
Result(s): Histologic and immunohistochemical identification of Hodgkin lymphoma within ovarian tissue harvested for cryopreservation.
Conclusion(s): Ovarian cryopreservation and subsequent autografting is a procedure still in an experimental phase that has yielded promising findings. This option is frequently offered to young women with neoplasms such as Hodgkin lymphoma. Although the risk of Hodgkin lymphoma infiltration into the ovary may be low, the identification of lymphoma in this case emphasizes the importance of histologic examination of ovarian tissue before freezing and indicates that there is a possibility of reintroducing tumor.
|Item Type:||Refereed Article|
|Keywords:||fertility preservation, histology, Hodgkin lymphoma, ovarian cryopreservation|
|Research Division:||Medical and Health Sciences|
|Research Group:||Oncology and Carcinogenesis|
|Research Field:||Cancer Diagnosis|
|Objective Group:||Clinical Health (Organs, Diseases and Abnormal Conditions)|
|Objective Field:||Cancer and Related Disorders|
|Author:||Harrup, R (Dr Rosemary Harrup)|
|Web of Science® Times Cited:||18|
|Deposited By:||Medicine (Discipline)|
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