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Recent advances in capillary electrophoretic migration techniques for pharmaceutical analysis (2013–2015)

Citation

El Deeb, S and Watzig, H and El-Hady, DA and Sanger-van de Griend, C and Scriba, GKE, Recent advances in capillary electrophoretic migration techniques for pharmaceutical analysis (2013-2015), Electrophoresis, 37, (12) pp. 1591-1608. ISSN 0173-0835 (2016) [Refereed Article]

Copyright Statement

Copyright 2016 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim

DOI: doi:10.1002/elps.201600058

Abstract

This review updates and follows-up a previous review by highlighting recent advancements regarding capillary electromigration methodologies and applications in pharmaceutical analysis. General approaches such as quality by design as well as sample injection methods and detection sensitivity are discussed. The separation and analysis of drug-related substances, chiral CE, and chiral CE-MS in addition to the determination of physicochemical constants are addressed. The advantages of applying affinity capillary electrophoresis in studying receptor–ligand interactions are highlighted. Finally, current aspects related to the analysis of biopharmaceuticals are reviewed. The present review covers the literature between January 2013 and December 2015.

Item Details

Item Type:Refereed Article
Keywords:biopharmaceuticals, capillary electrophoresis, pharmaceutical analysis, quantitation
Research Division:Chemical Sciences
Research Group:Analytical Chemistry
Research Field:Separation Science
Objective Division:Expanding Knowledge
Objective Group:Expanding Knowledge
Objective Field:Expanding Knowledge in the Chemical Sciences
Author:Sanger-van de Griend, C (Dr Cari Sanger)
ID Code:118146
Year Published:2016
Web of Science® Times Cited:25
Deposited By:Austn Centre for Research in Separation Science
Deposited On:2017-07-05
Last Modified:2017-10-13
Downloads:0

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