eCite Digital Repository

Systematic review: exercise-induced gastrointestinal syndrome - implications for health and intestinal disease

Citation

Costa, RJS and Snipe, RMJ and Kitic, C and Gibson, PR, Systematic review: exercise-induced gastrointestinal syndrome - implications for health and intestinal disease, Alimentary Pharmacology & Therapeutics, 46, (3) pp. 246-265. ISSN 0269-2813 (2017) [Refereed Article]

Copyright Statement

© 2017 John Wiley & Sons

DOI: doi:10.1111/apt.14157

Abstract

Background: "Exercise-induced gastrointestinal syndrome" refers to disturbances of gastrointestinal integrity and function that are common features of strenuous exercise.

Aim: To systematically review the literature to establish the impact of acute exercise on markers of gastrointestinal integrity and function in healthy populations and those with chronic gastrointestinal conditions.

Methods: Search literature using five databases (PubMed, EBSCO, Web of Science, SPORTSdiscus, and Ovid Medline) to review publications that focused on the impact of acute exercise on markers of gastrointestinal injury, permeability, endotoxaemia, motility and malabsorption in healthy populations and populations with gastrointestinal diseases/disorders.

Results: As exercise intensity and duration increases, there is considerable evidence for increases in indices of intestinal injury, permeability and endotoxaemia, together with impairment of gastric emptying, slowing of small intestinal transit and malabsorption. The addition of heat stress and running mode appears to exacerbate these markers of gastrointestinal disturbance. Exercise stress of ≥2 hours at 60% VO2max appears to be the threshold whereby significant gastrointestinal perturbations manifest, irrespective of fitness status. Gastrointestinal symptoms, referable to upper- and lower-gastrointestinal tract, are common and a limiting factor in prolonged strenuous exercise. While there is evidence for health benefits of moderate exercise in patients with inflammatory bowel disease or functional gastrointestinal disorders, the safety of more strenuous exercise has not been established.

Conclusions: Strenuous exercise has a major reversible impact on gastrointestinal integrity and function of healthy populations. The safety and health implications of prolonged strenuous exercise in patients with chronic gastrointestinal diseases/disorders, while hypothetically worrying, has not been elucidated and requires further investigation.

Item Details

Item Type:Refereed Article
Keywords:gastrointestinal, exercise, disease
Research Division:Medical and Health Sciences
Research Group:Human Movement and Sports Science
Research Field:Human Movement and Sports Science not elsewhere classified
Objective Division:Health
Objective Group:Specific Population Health (excl. Indigenous Health)
Objective Field:Specific Population Health (excl. Indigenous Health) not elsewhere classified
Author:Kitic, C (Dr Cecilia Kitic)
ID Code:117704
Year Published:2017
Web of Science® Times Cited:9
Deposited By:Health Sciences
Deposited On:2017-06-26
Last Modified:2018-01-09
Downloads:0

Repository Staff Only: item control page