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Demodex treatment in external ocular disease: the outcomes of a Tasmanian case series


Nicholls, SG and Oakley, CL and Tan, A and Vote, BJ, Demodex treatment in external ocular disease: the outcomes of a Tasmanian case series, International Ophthalmology, 36, (5) pp. 691-696. ISSN 0165-5701 (2016) [Refereed Article]

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Copyright 2016 Springer Science+Business Media Dordrecht

DOI: doi:10.1007/s10792-016-0188-5


Demodex species (spp.) have previously been implicated in the pathogenesis of blepharitis. This study aims to correlate improvement in symptoms of external ocular disease with treatment of underlying Demodex spp. This is a prospective, observational case series of patients with chronic external ocular disease. Demodicosis was confirmed by microscopic examination of epilated eyelashes. The main outcome measure was response to the treatment (5 % tee tree oil) in regard to change in subjective symptoms utilising a symptom-based patient questionnaire assessment. Overall patients had a good response to the treatment in terms of improvement or resolution of symptoms, with 91 % of patients reporting at least some improvement in symptoms. The treatment of underlying Demodex spp. appears to result in improvement of symptoms in patients with long standing external ocular disease and underlying Demodex spp. infestation.

Item Details

Item Type:Refereed Article
Keywords:Blepharitis, Demodex spp, Dry eye disease, External ocular disease, Tea tree oil
Research Division:Biomedical and Clinical Sciences
Research Group:Ophthalmology and optometry
Research Field:Ophthalmology
Objective Division:Health
Objective Group:Clinical health
Objective Field:Clinical health not elsewhere classified
UTAS Author:Nicholls, SG (Dr Stephen Nicholls)
ID Code:117614
Year Published:2016
Web of Science® Times Cited:20
Deposited By:Menzies Institute for Medical Research
Deposited On:2017-06-21
Last Modified:2017-10-24

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