Beare, RJ and Das, G and Ren, M and Chong, W and Sinnott, MD and Hilton, JE and Srikanth, V and Phan, TG, Does the principle of minimum work apply at the carotid bifurcation: a retrospective cohort study, BMC Medical Imaging, 11 Article 17. ISSN 1471-2342 (2011) [Refereed Article]
Copyright 2011 Beare et al. Licensed under Creative Commons Attribution 2.0 Generic (CC BY 2.0) https://creativecommons.org/licenses/by/2.0/
METHODS: This study involved subjects who had computed tomographic angiography (CTA) at our institution between 2006 and 2007. Radii of the common, internal and external carotid arteries were determined. The exponent was determined for individual bifurcations using numerical methods and for the sample using nonlinear regression.
RESULTS: Mean age for 45 participants was 56.9 ± 16.5 years with 26 males. Prevalence of vascular risk factors was: hypertension--48%, smoking--23%, diabetes--16.7%, hyperlipidemia--51%, ischemic heart disease--18.7%.The value of the exponent ranged from 1.3 to 1.6, depending on estimation methodology.
CONCLUSIONS: The principle of minimum work (defined by an exponent of 3) may not apply at the carotid bifurcation. Additional factors may play a role in the relationship between the radii of the parent and daughter vessels.
|Item Type:||Refereed Article|
|Research Division:||Medical and Health Sciences|
|Research Group:||Clinical Sciences|
|Research Field:||Radiology and Organ Imaging|
|Objective Group:||Clinical Health (Organs, Diseases and Abnormal Conditions)|
|Objective Field:||Cardiovascular System and Diseases|
|Author:||Srikanth, V (Dr Velandai Srikanth)|
|Web of Science® Times Cited:||5|
|Deposited By:||Menzies Institute for Medical Research|
|Downloads:||6 View Download Statistics|
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