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Establishing benchmark EQ-5D-3L population health state utilities and identifying their correlates in Gansu Province, China

journal contribution
posted on 2023-05-19, 05:57 authored by Lei SiLei Si, Shi, L, Chen, M, Andrew PalmerAndrew Palmer
Purposes: Despite a flurry of cost utility analyses conducted in the Chinese population in recent years, a standard set of health state utilities (HSUs) for the Chinese population is lacking. The aims of this study were to (1) determine benchmark age- and sex-specific HSUs for a Chinese population, and (2) assess key correlates of HSUs in this population.

Methods: Quality-of-life was evaluated using the validated EQ-5D-3L questionnaire. HSUs were calculated using data collected from Gansu Province (n = 9833). Overall differences in HSUs were analysed using linear regression and a two-tailed p value < 0.05 was determined to be statistically significant. The minimal difference in weighted index was set at 0.074.

Results: HSUs decreased with age in both males and females. Living in the non-capital areas, being separated/divorced/widowed or never married, being never educated, diagnosed with chronic disease, and no regular physical activity were associated with lower HSUs. HSUs for women were lower than for men in univariate regression analysis; however, no differences were found after adjusting for other covariates. In addition, the difference in HSU reached the level of minimal difference in weighted index for participants with chronic disease. HSUs for those who were diagnosed with chronic disease were 0.098 (0.092-0.104) lower than those without chronic disease.

Conclusions: This study reports HSUs for a Chinese population in Gansu and investigates the key correlates of HSUs in this population. In addition, the use of EQ-5D-3L in assessing population health is limited given the high ceiling effect and skewed HSUs.

History

Publication title

Quality of Life Research

Volume

26

Issue

11

Pagination

3049-3058

ISSN

0962-9343

Department/School

Menzies Institute for Medical Research

Publisher

Kluwer Academic Publ

Place of publication

Van Godewijckstraat 30, Dordrecht, Netherlands, 3311 Gz

Rights statement

copyright 2017 Springer International Publishing AG

Repository Status

  • Restricted

Socio-economic Objectives

Health status (incl. wellbeing)

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