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Human metallothionein gene MT1L mRNA is present in several human tissues but is unlikely to produce a metallothionein protein

Citation

Holloway, AF and Stennard, FA and West, AK, Human metallothionein gene MT1L mRNA is present in several human tissues but is unlikely to produce a metallothionein protein, FEBS Letters, 404, (1) pp. 41-44. ISSN 0014-5793 (1997) [Refereed Article]

DOI: doi:10.1016/S0014-5793(97)00082-3

Abstract

A human MT gene from the functional locus on Chromosome 16, MT1L, is characterised and shown to produce mRNA in at least four human tissues. This gene is unlikely to produce a metallothionein protein because it contains a termination codon at position 26, by analogy to other human MT1 genes. MT1L cDNA is almost identical to another metallothionein cDNA clone reported recently, MT1(R), suggesting that either there are unmapped human metallothionein genes, or that MT1L is polymorphic.

Item Details

Item Type:Refereed Article
Research Division:Biological Sciences
Research Group:Biochemistry and Cell Biology
Research Field:Cell Metabolism
Objective Division:Expanding Knowledge
Objective Group:Expanding Knowledge
Objective Field:Expanding Knowledge in the Environmental Sciences
Author:Holloway, AF (Associate Professor Adele Holloway)
Author:Stennard, FA (Dr Fiona Stennard)
Author:West, AK (Professor Adrian West)
ID Code:11704
Year Published:1997
Web of Science® Times Cited:4
Deposited By:Biochemistry
Deposited On:1997-08-01
Last Modified:2011-08-12
Downloads:0

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