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Effectiveness of a shared team approach between nurses and doctors for improved risk factor management in survivors of stroke: a cluster randomized controlled trial
Olaiya, MT and Kim, J and Nelson, MR and Srikanth, VK and Bladin, CF and Gerraty, RP and Fitzgerald, SM and Phan, T and Frayne, J and Cadilhac, DA and Thrift, AG, on behalf of the STANDFIRM investigators, Effectiveness of a shared team approach between nurses and doctors for improved risk factor management in survivors of stroke: a cluster randomized controlled trial, European Journal of Neurology, 24, (7) pp. 920-928. ISSN 1351-5101 (2017) [Refereed Article]
© 2017 EAN
Methods: This was a prospective, multicentre, cluster-randomized controlled trial with blinded assessment of outcomes and intention-to-treat analysis. Patients hospitalized for stroke/transient ischaemic attack and aged ≥18 years were recruited from four hospitals. General practices treating recruited patients were randomized to provide either usual care or an individualized management programme comprising nurse-led education and review of care plans by stroke specialists in addition to usual care. The primary outcome was a change in cardiovascular Framingham Risk Score between baseline and 12 months.
Results: From January 2010 to November 2013, 156 general practices (280 patients) were randomly assigned to usual care (control) and 159 (283 patients) to the intervention. The median age was 70.1 years; 65% were male. Overall, >80% of participants were prescribed recommended secondary prevention therapies at baseline. The primary efficacy analysis comprised 533 participants, with 30 either dying or lost to follow-up. In adjusted analyses, no significant between-group difference was found in the cardiovascular risk score at 12 months (0.04, 95% confidence interval -1.7, 1.8).
Conclusions: The effectiveness of an organized secondary prevention programme for stroke may be limited in patients from high-performing hospitals with regular post-discharge follow-up and communication with general practices.
|Item Type:||Refereed Article|
|Keywords:||randomized clinical trial, risk factors, secondary prevention, stroke, transient ischaemic attack|
|Research Division:||Biomedical and Clinical Sciences|
|Research Group:||Cardiovascular medicine and haematology|
|Research Field:||Cardiology (incl. cardiovascular diseases)|
|Objective Group:||Clinical health|
|Objective Field:||Clinical health not elsewhere classified|
|UTAS Author:||Nelson, MR (Professor Mark Nelson)|
|UTAS Author:||Srikanth, VK (Dr Velandai Srikanth)|
|Web of Science® Times Cited:||16|
|Deposited By:||Menzies Institute for Medical Research|
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