116000 Journal Article.pdf (295.77 kB)
Relevance of the T cell receptor-ligand avidity for immunity to infection
journal contribution
posted on 2023-05-22, 03:04 authored by Nauerth, M, Wing, K, Heinrich KornerHeinrich Korner, Busch, DHCytotoxic lymphocytes are critical for fighting viral and certain bacterial infections. Therefore, assessing the quality of cytotoxic T cell responses might have important clinical implications. TCR-pMHC binding (avidity) is a key determinant of T cell quality. Here we review currently available technologies for the measurement of TCR-pMHC avidity and their potential relevance for translational applications.
History
Publication title
Journal of Microbial & Biochemical TechnologyVolume
8Pagination
131-135ISSN
1948-5948Department/School
Menzies Institute for Medical ResearchPublisher
Omics Publishing GroupPlace of publication
United StatesRights statement
Copyright: © 2016 Nauerth M, et al. Licensed under Creative Commons Attribution 4.0 International (CC BY 4.0) https://creativecommons.org/licenses/by/4.0/Repository Status
- Open