Antony, B and Ding, C, Vitamin D deficiency in joint pain: Effects of vitamin D supplementation, Nutritional Modulators of Pain in the Aging Population, Academic Press, RR Watson, S Zibadi (ed), United States, pp. 183-189. ISBN 978-0-12-805186-3 (2017) [Research Book Chapter]
Copyright 2017 Elsevier Inc.
Results: There are inconsistent results from the observational studies that explored the association between vitamin D deficiency and joint pain relating to major musculoskeletal conditions. Some reported a weak, but statistically significant association with knee and hip joint pain and the association was apparent only in people with moderate vitamin D deficiency.
There are only a few randomized placebo-controlled trials that have explored the effect of vitamin D supplementation on joint pain. The available evidence suggests that there is no clinically significant benefit of vitamin D supplementation for knee pain. The nonrandomized clinical trials reported a small beneficial effect on joint pain.
Conclusion: The available evidence suggests that vitamin D supplementation may not have a significant effect on the management of joint pain.
|Item Type:||Research Book Chapter|
|Keywords:||vitamin D deficiency, joint pain, knee, hip, supplementation, musculoskeletal pain, osteoarthritis, rheumatoid arthritis|
|Research Division:||Medical and Health Sciences|
|Research Group:||Clinical Sciences|
|Research Field:||Rheumatology and Arthritis|
|Objective Group:||Clinical Health (Organs, Diseases and Abnormal Conditions)|
|Objective Field:||Skeletal System and Disorders (incl. Arthritis)|
|Author:||Antony, B (Dr Benny Eathakkattu Antony)|
|Author:||Ding, C (Professor Chang-Hai Ding)|
|Deposited By:||Menzies Institute for Medical Research|
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