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Vitamin D deficiency in joint pain: Effects of vitamin D supplementation


Antony, B and Ding, C, Vitamin D deficiency in joint pain: Effects of vitamin D supplementation, Nutritional Modulators of Pain in the Aging Population, Academic Press, RR Watson, S Zibadi (ed), United States, pp. 183-189. ISBN 978-0-12-805186-3 (2017) [Research Book Chapter]

Copyright Statement

Copyright 2017 Elsevier Inc.

DOI: doi:10.1016/B978-0-12-805186-3.00015-1


Objective: This chapter reviews the evidence of the role of vitamin D deficiency in joint pain and the effects of vitamin D supplementation on joint pain.

Results: There are inconsistent results from the observational studies that explored the association between vitamin D deficiency and joint pain relating to major musculoskeletal conditions. Some reported a weak, but statistically significant association with knee and hip joint pain and the association was apparent only in people with moderate vitamin D deficiency.

There are only a few randomized placebo-controlled trials that have explored the effect of vitamin D supplementation on joint pain. The available evidence suggests that there is no clinically significant benefit of vitamin D supplementation for knee pain. The nonrandomized clinical trials reported a small beneficial effect on joint pain.

Conclusion: The available evidence suggests that vitamin D supplementation may not have a significant effect on the management of joint pain.

Item Details

Item Type:Research Book Chapter
Keywords:vitamin D deficiency, joint pain, knee, hip, supplementation, musculoskeletal pain, osteoarthritis, rheumatoid arthritis
Research Division:Biomedical and Clinical Sciences
Research Group:Clinical sciences
Research Field:Rheumatology and arthritis
Objective Division:Health
Objective Group:Clinical health
Objective Field:Clinical health not elsewhere classified
UTAS Author:Antony, B (Dr Benny Eathakkattu Antony)
UTAS Author:Ding, C (Professor Chang-Hai Ding)
ID Code:115972
Year Published:2017
Deposited By:Menzies Institute for Medical Research
Deposited On:2017-04-24
Last Modified:2018-05-29

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