Fonseca, R and Otahal, P and Galligan, J and Neilson, S and Huynh, Q and Saito, M and Negishi, K and Marwick, TH, Association of survival time with transthoracic echocardiography in stable patients with heart failure: Is routine follow-up ever appropriate?, International Journal of Cardiology, 230 pp. 619-624. ISSN 0167-5273 (2017) [Refereed Article]
Copyright 2016 Elsevier Ireland Ltd.
METHODS: Patients with HF were selected from consecutive HF admissions from 2008 to 2012. Groups were divided into: no follow-up TTE; routine <1year with no change in status ("rarely appropriate"), ≥1year follow-up with no change in status ("maybe appropriate") and TTE due to change in clinical status ("appropriate"). Survival analysis was performed for the combined endpoint of HF readmission and death, and a separate analysis was performed for HF readmission, with death as a competing risk.
RESULTS: Of 550 HF patients, 141 had a follow-up TTE, including 41 (29%) within 1year. The event-free time in years was similar between no TTE (1.10years [95%CI: 0.69, 1.49], routine TTE <1year (2.61years [95% CI: 1.08, 3.04], routine >1year (2.45years [95% CI: 1.37, 5.78]); all were greater than symptomatic patients (0.09years [95% CI: 0.02, 1.80]). HF readmission was independently associated with statins, renal disease, coronary angiography and NYHA class, but not follow-up TTE timing. There were no differences in the cumulative incidence for death between groups. There were no differences in change in management in routine TTE <1year and ≥1year.
CONCLUSION: The distinction of appropriateness of routine repeat TTE in stable HF patients, based on testing <1 or ≥1year after index admission appears unjustified.
|Item Type:||Refereed Article|
|Keywords:||Appropriate use, Echocardiography, Heart failure|
|Research Division:||Medical and Health Sciences|
|Research Group:||Cardiorespiratory Medicine and Haematology|
|Research Field:||Cardiology (incl. Cardiovascular Diseases)|
|Objective Group:||Clinical Health (Organs, Diseases and Abnormal Conditions)|
|Objective Field:||Cardiovascular System and Diseases|
|Author:||Fonseca, R (Mr Ricardo Fonseca Diaz)|
|Author:||Otahal, P (Mr Petr Otahal)|
|Author:||Huynh, Q (Dr Quan Huynh)|
|Author:||Saito, M (Dr Makoto Saito)|
|Author:||Negishi, K (Dr Kazuaki Negishi)|
|Author:||Marwick, TH (Professor Tom Marwick)|
|Deposited By:||Menzies Institute for Medical Research|
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