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Muscular strength, aerobic capacity, and adipocytokines in obese youth after resistance training: A pilot study

Citation

Shultz, S and Dahiya, R and Leong, GM and Rowlands, DS and Hills, AP and Byrne, NM, Muscular strength, aerobic capacity, and adipocytokines in obese youth after resistance training: A pilot study, The Australasian medical journal, 8, (4) pp. 113-120. ISSN 1836-1935 (2015) [Refereed Article]

DOI: doi:10.4066/AMJ.2015.2293

Abstract

Background: Exercise has shown positive training effects on obesity-related inflammation, however, resistance training has shown mixed results concerning adipocytokine levels.

Aims: The purpose of this pilot study was to explore the effects of resistance training on blood adipocytokine concentrations in obese youth, with specific examination of the relationship between these biomarkers and improved fitness (i.e., aerobic capacity, muscular strength).

Methods: Fourteen obese adolescents (16.1 1.6 y; BMI: 32.3 3.9 kg/m2) participated in a 16-week resistance training intervention. Body composition, fasting blood concentrations of interleukin-6 (IL-6), tumour necrosis factor-alpha (TNF-ɑ), adiponectin, and leptin were measured pre- and post-training. Aerobic capacity was assessed via a maximal discontinuous exercise test. The rate of gain in muscular strength was calculated as the slope of progression in 1-repetition maximum throughout the intervention.

Results: Resistance training increased lean mass (total, trunk) and decreased per cent body fat (total, trunk). The training also caused moderate clear decreases in IL-6 and TNF-ɑ concentrations. A small increase in adiponectin was also observed before and after intervention. When the group was stratified by changes in aerobic capacity, there were substantially larger decreases in leptin levels for those with improved capacity. Correlation analyses also revealed a negative relationship between log-transformed leptin and aerobic capacity at rest. Improvement in quadriceps strength was positively correlated with IL-6 and TNF-ɑ, while improvement in shoulder adductor strength was positively correlated with IL-6 only.

Conclusion: Resistance training improved adipocytokine markers, which were partially associated with improved physical fitness. Specifically, the relationship between strength improvements and IL-6 and TNF-ɑ suggests an exercise-induced signalling pathway that results in overall adaptive decreases in systemic inflammation in obese youth.

Item Details

Item Type:Refereed Article
Keywords:Exercise, paediatric obesity, inflammation, fitness
Research Division:Medical and Health Sciences
Research Group:Human Movement and Sports Science
Research Field:Exercise Physiology
Objective Division:Expanding Knowledge
Objective Group:Expanding Knowledge
Objective Field:Expanding Knowledge in the Medical and Health Sciences
Author:Hills, AP (Professor Andrew Hills)
Author:Byrne, NM (Professor Nuala Byrne)
ID Code:115669
Year Published:2015
Deposited By:Health Sciences
Deposited On:2017-04-04
Last Modified:2017-10-31
Downloads:0

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