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Novel approaches to the treatment of hyperglycaemia in type 2 diabetes mellitus
journal contribution
posted on 2023-05-19, 02:42 authored by Galligan, A, Timothy GreenawayTimothy GreenawayControl of hyperglycaemia is a fundamental therapeutic goal in patients with type 2 diabetes. The progressive nature of β-cell dysfunction in type 2 diabetes leads to the need for escalating anti-hyperglycaemic treatment, including insulin, in most patients. Given the prevalence of complications such as weight gain and hypoglycaemia associated with traditional anti-hyperglycaemic agents (AHA), including sulphonylureas and insulin, it is unsurprising that recent years have seen the development of novel agents to treat hyperglycaemia. With increasing evidence supporting the need for a multi-faceted approach to the prevention of adverse cardiovascular events in people with type 2 diabetes, a patient-centred and individualised management strategy addressing lifestyle, cardiovascular risk factor modification and glycaemic control remains critical in improving outcomes in these patients.
History
Publication title
Internal Medicine JournalVolume
46Issue
5Pagination
540-549ISSN
1444-0903Department/School
Tasmanian School of MedicinePublisher
Blackwell Publishing AsiaPlace of publication
AustraliaRights statement
Copyright 2016 Royal Australasian College of PhysiciansRepository Status
- Restricted