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Novel approaches to the treatment of hyperglycaemia in type 2 diabetes mellitus


Galligan, A and Greenaway, TM, Novel approaches to the treatment of hyperglycaemia in type 2 diabetes mellitus, Internal Medicine Journal, 46, (5) pp. 540-549. ISSN 1444-0903 (2016) [Refereed Article]

Copyright Statement

Copyright 2016 Royal Australasian College of Physicians

DOI: doi:10.1111/imj.13070


Control of hyperglycaemia is a fundamental therapeutic goal in patients with type 2 diabetes. The progressive nature of β-cell dysfunction in type 2 diabetes leads to the need for escalating anti-hyperglycaemic treatment, including insulin, in most patients. Given the prevalence of complications such as weight gain and hypoglycaemia associated with traditional anti-hyperglycaemic agents (AHA), including sulphonylureas and insulin, it is unsurprising that recent years have seen the development of novel agents to treat hyperglycaemia. With increasing evidence supporting the need for a multi-faceted approach to the prevention of adverse cardiovascular events in people with type 2 diabetes, a patient-centred and individualised management strategy addressing lifestyle, cardiovascular risk factor modification and glycaemic control remains critical in improving outcomes in these patients.

Item Details

Item Type:Refereed Article
Keywords:type 2 diabetes, anti-hyperglycaemic agents, cardiovascular safety, novel and emerging therapies
Research Division:Biomedical and Clinical Sciences
Research Group:Clinical sciences
Research Field:Endocrinology
Objective Division:Health
Objective Group:Clinical health
Objective Field:Clinical health not elsewhere classified
UTAS Author:Greenaway, TM (Dr Tim Greenaway)
ID Code:114889
Year Published:2016
Web of Science® Times Cited:2
Deposited By:Medicine
Deposited On:2017-03-01
Last Modified:2022-08-29

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