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Novel approaches to the treatment of hyperglycaemia in type 2 diabetes mellitus

journal contribution
posted on 2023-05-19, 02:42 authored by Galligan, A, Timothy GreenawayTimothy Greenaway
Control of hyperglycaemia is a fundamental therapeutic goal in patients with type 2 diabetes. The progressive nature of β-cell dysfunction in type 2 diabetes leads to the need for escalating anti-hyperglycaemic treatment, including insulin, in most patients. Given the prevalence of complications such as weight gain and hypoglycaemia associated with traditional anti-hyperglycaemic agents (AHA), including sulphonylureas and insulin, it is unsurprising that recent years have seen the development of novel agents to treat hyperglycaemia. With increasing evidence supporting the need for a multi-faceted approach to the prevention of adverse cardiovascular events in people with type 2 diabetes, a patient-centred and individualised management strategy addressing lifestyle, cardiovascular risk factor modification and glycaemic control remains critical in improving outcomes in these patients.

History

Publication title

Internal Medicine Journal

Volume

46

Issue

5

Pagination

540-549

ISSN

1444-0903

Department/School

Tasmanian School of Medicine

Publisher

Blackwell Publishing Asia

Place of publication

Australia

Rights statement

Copyright 2016 Royal Australasian College of Physicians

Repository Status

  • Restricted

Socio-economic Objectives

Clinical health not elsewhere classified

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    University Of Tasmania

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