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Derivatisation for separation and detection in capillary electrophoresis (2012-2015)


Wuethrich, A and Quirino, JP, Derivatisation for separation and detection in capillary electrophoresis (2012-2015), Electrophoresis, 37, (1) pp. 45-55. ISSN 0173-0835 (2016) [Refereed Article]

Copyright Statement

Copyright 2015 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim

DOI: doi:10.1002/elps.201500290


Derivatisation is a well-established and mature form of sample preparation for CE. The modification of the analyte can cause superior analysis characteristics such as better sensitivity and selectivity, however, derivatisation of the analyte introduces an additional step into the analytical workflow. This review covers articles from January 2012 to January 2015 on derivatisation in CE. The main sections are on the derivatisation modes (i.e. pre-capillary, in-line, in-capillary and post-capillary), separation and detection modes (i.e. LIF and others). LIF is discussed in more detail since this detection mode was most prevalent. A table of the common labelling agents and wavelengths for excitation and emission and the common derivatisation reactions are included. In addition, a comprehensive table which summarises all research articles is provided. This review is suitable for analytical chemists as a guide for 'how to get started' with derivatisation for separation and detection in CE.

Item Details

Item Type:Refereed Article
Research Division:Chemical Sciences
Research Group:Analytical chemistry
Research Field:Separation science
Objective Division:Expanding Knowledge
Objective Group:Expanding knowledge
Objective Field:Expanding knowledge in the chemical sciences
UTAS Author:Wuethrich, A (Mr Alain Wuethrich)
UTAS Author:Quirino, JP (Associate Professor Lito Quirino)
ID Code:114843
Year Published:2016
Funding Support:Australian Research Council (FT100100213)
Web of Science® Times Cited:19
Deposited By:Chemistry
Deposited On:2017-02-28
Last Modified:2017-11-10

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