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Non-invasive brain stimulation improves paretic limb force production: a systematic review and meta-analysis

Citation

Kang, N and Summers, JJ and Cauraugh, H, Non-invasive brain stimulation improves paretic limb force production: a systematic review and meta-analysis, Brain stimulation, 9, (5) pp. 662-670. ISSN 1935-861X (2016) [Refereed Article]

Copyright Statement

Copyright 2016 Elsevier Inc.

DOI: doi:10.1016/j.brs.2016.05.005

Abstract

BACKGROUND: Non-invasive brain stimulation (NIBS) facilitates motor improvements post stroke. Transcranial direct current stimulation (tDCS) and repetitive transcranial magnetic stimulation (rTMS) are representative NIBS techniques frequently used in stroke motor rehabilitation. Our primary question is: Do these two techniques improve force production capability in paretic limbs?

OBJECTIVE: The current systematic review and meta-analysis investigated the effects of tDCS and rTMS on paretic limb force production in stroke survivors.

METHODS: Our comprehensive search identified 23 studies that reported changes in force production following tDCS or rTMS interventions. Each used random assignment and a sham control group. The 23 qualified studies in our meta-analysis generated 29 comparisons: 14 tDCS and 15 rTMS comparisons.

RESULTS: Random effects models indicated improvements in paretic limb force after tDCS and rTMS rehabilitation. We found positive effects on force production in the two sets of stimulation protocols: (a) increasing cortical activity in the ipsilesional hemisphere and (b) decreasing cortical activity in the contralesional hemisphere. Moreover, across acute, subacute, and chronic phases, tDCS and rTMS improved force production.

CONCLUSION: Cumulative meta-analytic results revealed that tDCS and rTMS rehabilitation protocols successfully improved paretic limb force production capabilities.

Item Details

Item Type:Refereed Article
Keywords:Force production; Meta-analysis; Repetitive transcranial magnetic stimulation (rTMS); Stroke; Systematic review; Transcranial direct current stimulation (tDCS)
Research Division:Medical and Health Sciences
Research Group:Human Movement and Sports Science
Research Field:Motor Control
Objective Division:Health
Objective Group:Clinical Health (Organs, Diseases and Abnormal Conditions)
Objective Field:Nervous System and Disorders
Author:Summers, JJ (Professor Jeffery Summers)
ID Code:114813
Year Published:2016
Web of Science® Times Cited:6
Deposited By:Psychology
Deposited On:2017-02-28
Last Modified:2017-11-08
Downloads:0

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