eCite Digital Repository
Direct production of microstructured surfaces for planar chromatography using 3D printing
Citation
Macdonald, NP and Currivan, SA and Tedone, L and Paull, B, Direct production of microstructured surfaces for planar chromatography using 3D printing, Analytical Chemistry, 89 pp. 2457-2463. ISSN 0003-2700 (2017) [Refereed Article]
Copyright Statement
Copyright 2017 American Chemical Society
DOI: doi:10.1021/acs.analchem.6b04546
Abstract
Through optimization of the printing process and orientation, a suitably developed surface area has been realized upon a 3D printed polymer substrate to facilitate chromatographic separations in a planar configuration. Using an Objet Eden 260VS 3D printer, polymer thin layer chromatography platforms were directly fabricated without any additional surface functionalization and successfully applied to the separation of various dye and protein mixtures. The print material was characterized using gas chromatography coupled to mass spectrometry and spectroscopic techniques such as infrared and Raman. Preliminary studies included the separation of colored dyes, whereby the separation performance could be visualized optically. Subsequent separations were achieved using fluorescent dyes and fluorescently tagged proteins. The separation of proteins was affected by differences in the isoelectric point (pI) and the ion exchange properties of the printed substrate. The simple chromatographic separations are the first achieved using an unmodified 3D printed stationary phase.
Item Details
Item Type: | Refereed Article |
---|---|
Keywords: | 3D printing, separation science, additive manufacturing, planar chromatography |
Research Division: | Chemical Sciences |
Research Group: | Analytical chemistry |
Research Field: | Separation science |
Objective Division: | Expanding Knowledge |
Objective Group: | Expanding knowledge |
Objective Field: | Expanding knowledge in the chemical sciences |
UTAS Author: | Macdonald, NP (Dr Niall Macdonald) |
UTAS Author: | Currivan, SA (Dr Sinead Currivan) |
UTAS Author: | Tedone, L (Ms Laura Tedone) |
UTAS Author: | Paull, B (Professor Brett Paull) |
ID Code: | 114789 |
Year Published: | 2017 |
Web of Science® Times Cited: | 33 |
Deposited By: | Austn Centre for Research in Separation Science |
Deposited On: | 2017-02-27 |
Last Modified: | 2018-03-27 |
Downloads: | 0 |
Repository Staff Only: item control page