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Pasteurellaceae bacteria from the oral cavity of Tasmanian devils (Sarcophilus Harrisii) show high minimum inhibitory concentration values towards aminoglycosides and clindamycin

Citation

Gutman, N and Hansen, MJ and Bertelsen, MF and Bojesen, AM, Pasteurellaceae bacteria from the oral cavity of Tasmanian devils (Sarcophilus Harrisii) show high minimum inhibitory concentration values towards aminoglycosides and clindamycin, Letters in Applied Microbiology, 62, (3) pp. 237-242. ISSN 0266-8254 (2016) [Refereed Article]

Copyright Statement

Copyright 2016 The Society for Applied Microbiology

DOI: doi:10.1111/lam.12545

Abstract

Threatened by Devil Facial Tumor Disease, the Tasmanian devil populations are vulnerable and decreasing. Additionally, the devils’ biting behaviour elevates their risk of acquiring bite wound infections caused by members of the bacterial Pasteurellaceae family that are natural inhabitants of the oral microbiota. In medical management of such bite wounds, antimicrobial susceptibility profiles are crucial. Prior to this investigation, no available data on minimal inhibitory concentration (MIC) values existed. A total of 26 isolates obtained from the oral cavity of 26 healthy Tasmanian devils were tested for their antimicrobial susceptibility by broth micro dilution. Most prominently, high MIC values for clindamycin (≥4 μg ml−1), gentamicin (≥8 μg ml−1) and amikacin (≥32 μg ml−1), were observed for 92, 77 and 73% of the strains tested respectively. This study may be used as a guideline for antimicrobial therapy against bite wound infections caused by Pasteurellaceae originating from the oral cavity of Tasmanian devils.

Item Details

Item Type:Refereed Article
Keywords:antimicrobial susceptibility, MIC, minimum inhibitory concentration, Pasteurellaceae, Sarcophilus harrisii, Tasmanian devil
Research Division:Biological Sciences
Research Group:Zoology
Research Field:Animal Immunology
Objective Division:Environment
Objective Group:Flora, Fauna and Biodiversity
Objective Field:Flora, Fauna and Biodiversity of environments not elsewhere classified
Author:Hansen, MJ (Dr Mie Hansen)
ID Code:114671
Year Published:2016
Deposited By:Centre for Ecology and Biodiversity
Deposited On:2017-02-23
Last Modified:2017-11-08
Downloads:0

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