Pridmore, S and Erger, S and Rybak, M and Kelly, E and Lawson, F, Early relapse treatment (ERT) or 'maintenance' transcranial magnetic stimulation (TMS)?, American Journal of Medical Research, 4, (1) pp. 111-117. ISSN 2334-4814 (2017) [Refereed Article]
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Background: Major depressive disorder (MDD) commonly takes a relapsing form. Transcranial magnetic stimulation (TMS) has be suggested as a means of maintaining remission. Brief courses of TMS at about monthly intervals appear to provide health benefits.
Objective: To examine whether such brief courses of TMS are better conceptualized as maintaining remission, or as the provision of early relapse treatment.
Method: 25 series of treatment (18 different patients) were considered. Pre- and post-treatment 6-item Hamilton Depression Rating Scale (HAMD6) and 7 visual analogue scales (VASs) were collected, along with pretreatment Clinical Global Impression-Severity (CGI-S) and post-treatment CGIImprovement (I).
Results: Pre-treatment HAMD6 and CGI-S indicated that many patients were symptomatic and in early relapse. Post-treatment HAMD6 indicated that many patients had achieved remission, and this was supported by the CGI-I. The VAS scores also improved. Conclusions: Short courses of TMS at about monthly intervals have beneficial results and are better conceptualized as early relapse treatment (ERT).
|Item Type:||Refereed Article|
|Keywords:||major depressive disorder; transcranial magnetic stimulation; early relapse treatment|
|Research Division:||Medical and Health Sciences|
|Research Group:||Public Health and Health Services|
|Research Field:||Mental Health|
|Objective Group:||Public Health (excl. Specific Population Health)|
|Objective Field:||Mental Health|
|Author:||Pridmore, S (Professor Saxby Pridmore)|
|Deposited By:||Medicine (Discipline)|
|Downloads:||19 View Download Statistics|
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