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Early relapse treatment (ERT) or “maintenance” transcranial magnetic stimulation (TMS)?


Pridmore, S and Erger, S and Rybak, M and Kelly, E and Lawson, F, Early relapse treatment (ERT) or 'maintenance' transcranial magnetic stimulation (TMS)?, American Journal of Medical Research, 4, (1) pp. 111-117. ISSN 2334-4814 (2017) [Refereed Article]


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Background: Major depressive disorder (MDD) commonly takes a relapsing form. Transcranial magnetic stimulation (TMS) has be suggested as a means of maintaining remission. Brief courses of TMS at about monthly intervals appear to provide health benefits.

Objective: To examine whether such brief courses of TMS are better conceptualized as maintaining remission, or as the provision of early relapse treatment.

Method: 25 series of treatment (18 different patients) were considered. Pre- and post-treatment 6-item Hamilton Depression Rating Scale (HAMD6) and 7 visual analogue scales (VASs) were collected, along with pretreatment Clinical Global Impression-Severity (CGI-S) and post-treatment CGIImprovement (I).

Results: Pre-treatment HAMD6 and CGI-S indicated that many patients were symptomatic and in early relapse. Post-treatment HAMD6 indicated that many patients had achieved remission, and this was supported by the CGI-I. The VAS scores also improved. Conclusions: Short courses of TMS at about monthly intervals have beneficial results and are better conceptualized as early relapse treatment (ERT).

Item Details

Item Type:Refereed Article
Keywords:major depressive disorder, transcranial magnetic stimulation, early relapse treatment
Research Division:Health Sciences
Research Group:Health services and systems
Research Field:Mental health services
Objective Division:Health
Objective Group:Public health (excl. specific population health)
Objective Field:Mental health
UTAS Author:Pridmore, S (Professor Saxby Pridmore)
ID Code:114090
Year Published:2017
Deposited By:Medicine
Deposited On:2017-02-06
Last Modified:2018-08-27
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