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UiO-66@SiO2 core–shell microparticles as stationary phases for the separation of small organic molecules


Arrua, RD and Peristyy, A and Nesterenko, PN and Das, A and D'Alessandro, DM and Hilder, EF, UiO-66@SiO2 core-shell microparticles as stationary phases for the separation of small organic molecules, Analyst, 142 pp. 517-524. ISSN 0003-2654 (2017) [Refereed Article]

Copyright Statement

Copyright 2017 The Royal Society of Chemistry

DOI: doi:10.1039/c6an02344d


Composite particles containing the Zr-based metal–organic framework (MOF) UiO-66 were prepared using microwave-assisted solvothermal synthesis. Scanning electron microscopy, infrared spectroscopy, powder X-ray diffraction and nitrogen physisorption studies confirmed the deposition of 100–300 nm microporous particles with the UiO-66 topology on the surface of mesoporous 5 μm and non-porous 2.1 μm silica particles. The core–shell particles exhibited a unique flow-dependent separation selectivity (FDSS) effect which allows changes in both the retention and separation selectivity of small molecules by simple variation of the mobile phase flow rate under isocratic conditions. The impact of the loading of UiO-66 as well as the porosity of the underlying silica core (mesoporous and non-porous) on the FDSS effect was evaluated. The prepared adsorbents were also tested for the normal-phase (NP) and reversed-phase (RP) separation of xylene isomers, substituted benzenes and polyaromatic hydrocarbons (PAHs). Efficiencies of up to 32400 plates per m (styrene, k 1.59) and 37200 plates per m (anisole, k 2.90) were achieved under NP and RP modes, respectively. The results demonstrate the potential of novel MOF-based stationary phases for the separation of closely related compounds (e.g. positional isomers).

Item Details

Item Type:Refereed Article
Keywords:high performance liquid chromatography, metal-organic framework, flow selectivity
Research Division:Chemical Sciences
Research Group:Analytical chemistry
Research Field:Separation science
Objective Division:Expanding Knowledge
Objective Group:Expanding knowledge
Objective Field:Expanding knowledge in the chemical sciences
UTAS Author:Arrua, RD (Dr Dario Arrua)
UTAS Author:Peristyy, A (Dr Anton Peristyy)
UTAS Author:Nesterenko, PN (Professor Pavel Nesterenko)
UTAS Author:Hilder, EF (Professor Emily Hilder)
ID Code:113952
Year Published:2017
Funding Support:Australian Research Council (DP150102608)
Web of Science® Times Cited:44
Deposited By:Austn Centre for Research in Separation Science
Deposited On:2017-01-30
Last Modified:2022-08-22

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