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Associations among Visceral Obesity, Type 2 Diabetes, and Dementia
Citation
Heiss, CJ and Goldberg, LR, Associations among Visceral Obesity, Type 2 Diabetes, and Dementia, Journal of Obesity & Eating Disorders, 2, (2:17) pp. 1-5. ISSN 2471-8203 (2016) [Refereed Article]
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Copyright Statement
Copyright 2016 Heiss, CJ et al. Licensed under Creative Commons Attribution 4.0 International (CC BY 4.0) https://creativecommons.org/licenses/by/4.0/
DOI: doi:10.21767/2471-8513.100027
Abstract
Obesity is a recognized global epidemic. Obese individuals
are at increased risk for type 2 diabetes mellitus (T2DM),
and both obesity and diabetes are known risk factors for
dementia, another global public health issue. This paper
reviews research on the link between obesity, and
dementia, with an emphasis on visceral obesity. Some
obese individuals, the metabolically healthy obese, do not
appear to be at increased risk from excess body fat, but
most eventually become metabolically unhealthy over time.
Accumulation of visceral fat appears to be particularly
problematic. Visceral obesity results in increased free fatty
acid delivery to the liver, which, in turn, increases insulin
resistance. Visceral obesity is associated with increased
inflammatory adipokines which can promote cardiovascular
disease and dementia. In addition, a long term complication
of T2DM is dementia, due to the vascular complications and
increased inflammatory status associated with the disease.
These issues highlight the need for health professionals to
work to prevent and treat obesity, especially visceral
obesity, to optimize health and decrease the likelihood of
developing debilitating chronic diseases such as T2DM and
dementia. The Mediterranean diet may be useful in
decreasing inflammation and dementia risk. Other dietary
factors that reduce inflammation, insulin resistance, and
cardiovascular risk (and thus dementia) independent of
weight loss are addressed.
Item Details
| Item Type: | Refereed Article |
|---|---|
| Keywords: | Dementia, Type 2 Diabetes Mellitus, elevated blood glucose, insulin resistance, visceral fat, obesity |
| Research Division: | Medical and Health Sciences |
| Research Group: | Public Health and Health Services |
| Research Field: | Health Promotion |
| Objective Division: | Health |
| Objective Group: | Health and Support Services |
| Objective Field: | Health Education and Promotion |
| Author: | Goldberg, LR (Dr Lyn Goldberg) |
| ID Code: | 113317 |
| Year Published: | 2016 |
| Deposited By: | Wicking Dementia Research and Education Centre |
| Deposited On: | 2016-12-20 |
| Last Modified: | 2017-06-06 |
| Downloads: | 6 View Download Statistics |
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