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Print me an organ? Ethical and regulatory issues emerging from 3D bioprinting in medicine
journal contribution
posted on 2023-05-19, 00:11 authored by Frederic GilbertFrederic Gilbert, O'Connell, CD, Mladenovska, T, Susan DoddsRecent developments of three-dimensional printing of biomaterials (3D bioprinting) in medicine have been portrayed as demonstrating the potential to transform some medical treatments, including providing new responses to organ damage or organ failure. However, beyond the hype and before 3D bioprinted organs are ready to be transplanted into humans, several important ethical concerns and regulatory questions need to be addressed. This article starts by raising general ethical concerns associated with the use of bioprinting in medicine, then focus on more particular ethical issues related to experimental testing on humans, and the lack of current international regulatory directives to guide these experiments. Accordingly, this article 1) considers whether there is a limit as to what should be bioprinted in medicine; 2) examines key risks of significant harm associated with testing 3D bioprinting in humans; 3) investigates the clinical trial paradigm used to test 3D bioprinting; 4) analyses ethical questions of irreversibility, loss of treatment opportunity and replicability; 5) explores the current lack of a specific framework for regulating and testing 3D bioprinting treatments.
Funding
Australian Research Council
History
Publication title
Science and Engineering EthicsVolume
24Pagination
73-91ISSN
1353-3452Department/School
College Office - College of Arts, Law and EducationPublisher
Springer New York LLCPlace of publication
USARights statement
Copyright 2017 Springer Science+Business Media DordrechtRepository Status
- Restricted