The valuable glycoside asperuloside was efficiently isolated in multigram quantities from Coprosma quadrifida employing a recently developed rapid pressurised hot water extraction (PHWE) method that utilises an unmodified household espresso machine. This study represents the first time C. quadrifida has been extracted and its major chemical components isolated and analysed. Our findings reveal that this species is a rich source of asperuloside (7.0% yield w/w). Significantly, this represents one of the highest yields obtained of this glycoside from a Coprosma species, and the entire Rubiaceae family more generally.

Item Type:	Refereed Article
Keywords:	natural products, pressurised hot water extraction, iridoid glycoside
Research Division:	Chemical Sciences
Research Group:	Organic chemistry
Research Field:	Organic chemical synthesis
Objective Division:	Expanding Knowledge
Objective Group:	Expanding knowledge
Objective Field:	Expanding knowledge in the chemical sciences
UTAS Author:	Deans, BJ (Miss Bianca Deans)
UTAS Author:	Bissember, AC (Associate Professor Alex Bissember)
UTAS Author:	Smith, JA (Associate Professor Jason Smith)
ID Code:	112571
Year Published:	2016
Web of Science® Times Cited:	11
Deposited By:	Chemistry
Deposited On:	2016-11-16
Last Modified:	2018-03-14
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