eCite Digital Repository
Fibre-based electrofluidics on low cost versatile 3D printed platforms for solute delivery, separations and diagnostics; from small molecules to intact cells
Citation
Cabot, JM and Macdonald, NP and Phung, SC and Breadmore, MC and Paull, B, Fibre-based electrofluidics on low cost versatile 3D printed platforms for solute delivery, separations and diagnostics; from small molecules to intact cells, Analyst, 141, (23) pp. 6422-6431. ISSN 0003-2654 (2016) [Refereed Article]
Copyright Statement
Copyright 2016 The Royal Society of Chemistry
Abstract
A novel and effective fibre-based microfluidic methodology was developed to move and isolate charged
solutes, biomolecules, and intact bacterial cells, based upon a novel multi-functional 3D printed supporting
platform, with potential applications in the fields of microfluidics and biodiagnostics. Various on-fibre
electrophoretic techniques are demonstrated to separate, pre-concentrate, move, split, or cut and collect
the isolated zones of target solutes, including proteins and live bacterial cells. The use of knotting to link
different fibre materials, and the unique ability of this approach to physically concentrate solutes in
different locations are shown such that the concentrated solutes can be physically isolated and easily
transferred to other fibres. Application of this novel fibre-based technique within a potential diagnostic
platform for urinary tract infection is shown, together with the post-electrophoretic incubation of live
bacterial cells, demonstrating the cell survival following on-fibre electrophoretic concentration.
Item Details
Item Type: | Refereed Article |
---|---|
Keywords: | Fibre microfluidics, electrophoresis, bacteria, urinary tract infetion, trap live cells |
Research Division: | Chemical Sciences |
Research Group: | Analytical chemistry |
Research Field: | Bioassays |
Objective Division: | Expanding Knowledge |
Objective Group: | Expanding knowledge |
Objective Field: | Expanding knowledge in the chemical sciences |
UTAS Author: | Cabot, JM (Dr Joan Cabot Canyelles) |
UTAS Author: | Macdonald, NP (Dr Niall Macdonald) |
UTAS Author: | Phung, SC (Ms Sui Phung) |
UTAS Author: | Breadmore, MC (Professor Michael Breadmore) |
UTAS Author: | Paull, B (Professor Brett Paull) |
ID Code: | 112411 |
Year Published: | 2016 |
Web of Science® Times Cited: | 20 |
Deposited By: | Chemistry |
Deposited On: | 2016-11-09 |
Last Modified: | 2017-10-31 |
Downloads: | 0 |
Repository Staff Only: item control page