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Costs associated with hereditary haemochromatosis in Australia: a cost-of-illness study

Citation

de Graaff, B and Neil, A and Sanderson, K and Yee, KC and Palmer, AJ, Costs associated with hereditary haemochromatosis in Australia: a cost-of-illness study, Australian Health Review, 41, (3) pp. 254-267. ISSN 0156-5788 (2017) [Refereed Article]

Copyright Statement

Journal compilation copyright AHHA 2016

DOI: doi:10.1071/AH15188

Abstract

Objective: The aim of the present study was to assess health sector, other sector and time-related (productivity) costs associated with hereditary haemochromatosis from societal, government and patient perspectives for the Australian setting.

Methods: A national web-based survey of people with haemochromatosis was conducted between November 2013 and February 2015. Participants completed a health survey and resource use diaries. Costs were calculated using a bottom-up approach and calculated in 2015 Australian dollars.

Results: Cost data were available for 157 participants. From a societal perspective, the estimated annual cost of haemochromatosis was A$274 million. The mean (95% confidence interval) cost for symptomatic patients was almost threefold greater than that of asymptomatic patients (A$10 030 (770512670) vs A$3701 (24235296) respectively). Health sector and productivity-related time loss were the main cost drivers. When extrapolating costs to the Australian population level, asymptomatic haemochromatosis accounted for higher costs than symptomatic haemochromatosis (A$183 million vs A$91 million), reflecting the low clinical penetrance estimate used. Total costs increased when higher clinical penetrance estimates were used.

Conclusion: The present cost-of-illness study, the first to be published for haemochromatosis, found that although costs were substantial, they could be decreased by reducing clinical penetrance. Development of cost-effective strategies to increase early diagnosis is likely to result in better health outcomes for patients and lower total costs.

Item Details

Item Type:Refereed Article
Keywords:Haemochromatosis, cost of illness
Research Division:Economics
Research Group:Applied Economics
Research Field:Health Economics
Objective Division:Health
Objective Group:Public Health (excl. Specific Population Health)
Objective Field:Substance Abuse
Author:de Graaff, B (Ms Barbara de Graaff)
Author:Neil, A (Dr Amanda Neil)
Author:Sanderson, K (Associate Professor Kristy Sanderson)
Author:Yee, KC (Dr Kwang Yee)
Author:Palmer, AJ (Professor Andrew Palmer)
ID Code:111757
Year Published:2017 (online first 2016)
Web of Science® Times Cited:1
Deposited By:Menzies Institute for Medical Research
Deposited On:2016-10-05
Last Modified:2017-12-07
Downloads:0

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