de Graaff, B and Neil, A and Sanderson, K and Yee, KC and Palmer, AJ, Costs associated with hereditary haemochromatosis in Australia: a cost-of-illness study, Australian Health Review, 41, (3) pp. 254-267. ISSN 0156-5788 (2017) [Refereed Article]
Journal compilation copyright AHHA 2016
Methods: A national web-based survey of people with haemochromatosis was conducted between November 2013 and February 2015. Participants completed a health survey and resource use diaries. Costs were calculated using a bottom-up approach and calculated in 2015 Australian dollars.
Results: Cost data were available for 157 participants. From a societal perspective, the estimated annual cost of haemochromatosis was A$274 million. The mean (95% confidence interval) cost for symptomatic patients was almost threefold greater than that of asymptomatic patients (A$10 030 (7705–12670) vs A$3701 (2423–5296) respectively). Health sector and productivity-related time loss were the main cost drivers. When extrapolating costs to the Australian population level, asymptomatic haemochromatosis accounted for higher costs than symptomatic haemochromatosis (A$183 million vs A$91 million), reflecting the low clinical penetrance estimate used. Total costs increased when higher clinical penetrance estimates were used.
Conclusion: The present cost-of-illness study, the first to be published for haemochromatosis, found that although costs were substantial, they could be decreased by reducing clinical penetrance. Development of cost-effective strategies to increase early diagnosis is likely to result in better health outcomes for patients and lower total costs.
|Item Type:||Refereed Article|
|Keywords:||Haemochromatosis, cost of illness|
|Research Group:||Applied Economics|
|Research Field:||Health Economics|
|Objective Group:||Public Health (excl. Specific Population Health)|
|Objective Field:||Substance Abuse|
|Author:||de Graaff, B (Ms Barbara de Graaff)|
|Author:||Neil, A (Dr Amanda Neil)|
|Author:||Sanderson, K (Associate Professor Kristy Sanderson)|
|Author:||Yee, KC (Dr Kwang Yee)|
|Author:||Palmer, AJ (Professor Andrew Palmer)|
|Year Published:||2017 (online first 2016)|
|Web of Science® Times Cited:||2|
|Deposited By:||Menzies Institute for Medical Research|
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