Siejka, D and Taylor, B and Ponsonby, A-L and Dwyer, T and van der Mei, I, Association between exposure to farm animals and pets and risk of Multiple Sclerosis, Multiple Sclerosis and Related Disorders, 10 pp. 53-56. ISSN 2211-0348 (2016) [Refereed Article]
© 2016 Elsevier
Methods: Population based case-control study with 136 clinically definite MS cases and 272 controls randomly chosen from the community matched on sex and age. Data was collected from both questionnaire and a lifetime calendar detailing residence, occupation and pet/animal exposure over the course of participant's lives.
Results: Exposure to farming, livestock, specific farm animals and remoteness of residence showed no significant association with MS risk. Exposure to cats prior to disease onset was associated with a greater risk of MS (Adjusted Odds Ratio 2.46 (1.17–5.18)) but without a clear dose-response (test for trend, p=0.76).
Conclusions: In contrast to other literature, farming and exposure to farm animals were not associated with MS. While we identified an association between cat exposure and MS, there was no dose-response relationship, and previous studies showed inconsistent results, leaving us to conclude that there is no strong evidence that exposure to cats is associated with MS.
|Item Type:||Refereed Article|
|Keywords:||Case-control study, Cat, Dog, Farm animals, Multiple Sclerosis, Pets, Remoteness, Risk factor|
|Research Division:||Biomedical and Clinical Sciences|
|Research Field:||Central nervous system|
|Objective Group:||Clinical health|
|Objective Field:||Clinical health not elsewhere classified|
|UTAS Author:||Siejka, D (Mr Dylan Siejka)|
|UTAS Author:||Taylor, B (Professor Bruce Taylor)|
|UTAS Author:||van der Mei, I (Professor Ingrid van der Mei)|
|Web of Science® Times Cited:||5|
|Deposited By:||Menzies Institute for Medical Research|
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