eCite Digital Repository

Treatment of hypergranulation tissue in burn wounds with topical steroid dressings: a case series


Jaeger, M and Harats, M and Kornhaber, R and Aviv, U and Zerach, A and Haik, J, Treatment of hypergranulation tissue in burn wounds with topical steroid dressings: a case series, International Medical Case Reports Journal, 9 pp. 241-245. ISSN 1179-142X (2016) [Refereed Article]


Copyright Statement

Copyright 2016 Jaeger et al. Licensed under Creative Commons Attribution-NonCommercial 3.0 Unported (CC BY-NC 3.0)

DOI: doi:10.2147/IMCRJ.S113182


Hypergranulation tissue (or also known as overgranulation) may negatively influence burn wound healing time and contribute to recurrence of contractures in burn wounds and grafts. Subsequently, the treatment of hypergranulation tissue remains controversial and problematic. In this case series, we aimed to examine the feasibility and document the use of topical hydrocortisone in the treatment of hypergranulation tissue formation resulting from burn wounds. We report five cases where hypergranulation tissue developed following deep dermal/full-thickness burns. Initial burn wound treatment included necrotic tissue debridement, wound cleansing, and Flaminal®. All five cases underwent surgical debridement and split-skin ­grafting. Upon identification of hypergranulation tissue, hydrocortisone acetate 0.25% was applied ­topically as usual care for the treatment of hypergranulation tissue. All five patients had deep dermal/full-thickness burns with a total body surface area ranging from 22% to 61% and were aged from 3–41 years. All five cases developed hypergranulation tissue during their admission after debridement and split-thickness skin grafts. All patients showed an improvement in the treated areas with a complete regression of hypergranulation tissue and closure of the burn wounds. No clinically apparent local or systemic side effects of the treatment were observed. Topical hydrocortisone can be utilized as an effective, inexpensive, and noninvasive practical option in the treatment of hypergranulation tissue resulting from burn wounds.

Item Details

Item Type:Refereed Article
Keywords:hypergranulation, overgranulation, proud flesh, burns, hydrocortisone, wound healing
Research Division:Biomedical and Clinical Sciences
Research Group:Clinical sciences
Research Field:Surgery
Objective Division:Health
Objective Group:Provision of health and support services
Objective Field:Nursing
UTAS Author:Kornhaber, R (Dr Rachel Kornhaber)
ID Code:110800
Year Published:2016
Web of Science® Times Cited:13
Deposited By:Health Sciences
Deposited On:2016-08-15
Last Modified:2018-02-06
Downloads:171 View Download Statistics

Repository Staff Only: item control page