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Age, muscle fatigue, and walking endurance in pre-menopausal women


Hunter, GR and Bickel, CS and Del Corral, P and Byrne, NM and Hills, AP and Larson-Meyer, DE and Banman, MM and Newcomer, BR, Age, muscle fatigue, and walking endurance in pre-menopausal women, European Journal of Applied Physiology, 111, (4) pp. 715-723. ISSN 1439-6319 (2011) [Refereed Article]

Copyright Statement

Copyright 2010 Springer-Verlag

DOI: doi:10.1007/s00421-010-1694-1


Aging is associated with loss of endurance; however, aging is also associated with decreased fatigue during maximal isometric contractions. The aims of this study were to examine the relationship between age and walking endurance (WE) and maximal isometric fatigue (MIF) and to determine which metabolic/fitness components explain the expected age effects on WE and MIF. Subjects were 96 pre-menopausal women. Oxygen uptake (walking economy) was assessed during a 3-mph walk; aerobic capacity and WE by progressive treadmill test; knee extension strength by isometric contractions, MIF during a 90-s isometric plantar flexion (muscle metabolism measured by 31P MRS). Age was related to increased walking economy (low VO2, r = −0.19, P < 0.03) and muscle metabolic economy (force/ATP, 0.34, P = 0.01), and reduced MIF (−0.26, P < 0.03). However, age was associated with reduced WE (−0.28, P < 0.01). Multiple regression showed that muscle metabolic economy explained the age-related decrease in MIF (partial r for MIF and age −0.13, P = 0.35) whereas walking economy did not explain the age-related decrease in WE (partial r for WE and age −0.25, P < 0.02). Inclusion of VO2max and knee endurance strength accounted for the age-related decreased WE (partial r for WE and age = 0.03, P > 0.80). In premenopausal women, age is related to WE and MIF. In addition, these results support the hypothesis that age-related increases in metabolic economy may decrease MIF. However, decreased muscle strength and oxidative capacity are related to WE.

Item Details

Item Type:Refereed Article
Keywords:exercise economy, oxygen uptake, muscular strength, function
Research Division:Health Sciences
Research Group:Sports science and exercise
Research Field:Exercise physiology
Objective Division:Health
Objective Group:Specific population health (excl. Indigenous health)
Objective Field:Women's and maternal health
UTAS Author:Byrne, NM (Professor Nuala Byrne)
UTAS Author:Hills, AP (Professor Andrew Hills)
ID Code:110760
Year Published:2011
Web of Science® Times Cited:3
Deposited By:Health Sciences
Deposited On:2016-08-12
Last Modified:2017-12-15

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