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The Effect of Lorazepam on Long-Term Verbal Recall in Heavy and Light Social Drinkers

Citation

Nichols, JM and Martin, F, The Effect of Lorazepam on Long-Term Verbal Recall in Heavy and Light Social Drinkers, Alcohol, 14, (5) pp. 455-461. ISSN 0741-8329 (1997) [Refereed Article]

DOI: doi:10.1016/S0741-8329(96)00210-8

Abstract

Two experiments investigated long-term verbal memory performance in groups of 20-year-old heavy (HSDs) and light social drinkers (LSDs), in the presence and absence of a pharmacological challenge (lorazepam 2 mg). In Experiment 1 (n = 13), a verbal learning task was presented visually and it was found that lorazepam significantly impaired delayed verbal recall performance in both groups. Experiment 2 (n = 14) assessed the effect of presenting the verbal learning task in the auditory compared to the visual modality. Both groups' performance on the delayed trials of the visually presented task was reduced in the lorazepam treatment. However, in the auditory presented task, lorazepam reduced 30-min delayed recall performance in the HSDs but not in the LSDs. The differential effect of lorazepam on HSDs compared to LSDs on delayed recall performance when material is presented in the auditory modality may suggest that frequent heavy social drinking results in changes in CNS functioning.

Item Details

Item Type:Refereed Article
Research Division:Psychology and Cognitive Sciences
Research Group:Psychology
Research Field:Biological Psychology (Neuropsychology, Psychopharmacology, Physiological Psychology)
Objective Division:Health
Objective Group:Other Health
Objective Field:Health not elsewhere classified
Author:Nichols, JM (Ms Jennifer Nichols)
Author:Martin, F (Associate Professor Frances Martin)
ID Code:11067
Year Published:1997
Web of Science® Times Cited:3
Deposited By:Psychology
Deposited On:1997-08-01
Last Modified:2011-08-11
Downloads:0

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