Neale, RE and Armstrong, BK and Baxter, C and Duarte Romero, B and Ebeling, P and English, DR and Kimlin, MG and McLeod, DSA and O'Connell, RL and van der Pols, JC and Venn, AJ and Webb, PM and Whiteman, DC and Wockner, L, The D-Health Trial: A randomized trial of vitamin D for prevention of mortality and cancer, Contemporary Clinical Trials, 48 pp. 83-90. ISSN 1551-7144 (2016) [Refereed Article]
Copyright 2016 Elsevier Inc.
RESULTS: We recruited 21,315 participants to the trial between February 2014 and May 2015. The participants in the two arms of the trial were well-balanced at baseline. Comparison with Australian population statistics shows that the trial participants were less likely to report being in fair or poor health, to be current smokers or to have diabetes than the Australian population. However, the proportion overweight or with health conditions such as arthritis and angina was similar.
CONCLUSIONS: Observational data cannot be considered sufficient to support interventions delivered at a population level. Large-scale randomized trials such as the D-Health Trial are needed to inform public health policy and practice.
|Item Type:||Refereed Article|
|Keywords:||Cancer, Mortality, Randomized clinical trial, Vitamin D|
|Research Division:||Medical and Health Sciences|
|Research Group:||Public Health and Health Services|
|Objective Group:||Clinical Health (Organs, Diseases and Abnormal Conditions)|
|Objective Field:||Cancer and Related Disorders|
|Author:||Venn, AJ (Professor Alison Venn)|
|Web of Science® Times Cited:||6|
|Deposited By:||Menzies Institute for Medical Research|
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