BACKGROUND: New techniques that measure central blood pressure (BP) using an upper arm cuff-based approach require performance assessment. The aim of this study was to compare a cuff-based device (Cuff_CBP) to estimate central BP indices (systolic BP (SBP), diastolic BP (DBP), pulse pressure (PP), augmentation pressure (AP), augmentation index (AIx)) with noninvasive radial tonometry (Ton_CBP).

METHODS: Consecutive Cuff_CBP (SphygmoCor Xcel) and Ton_CBP (SphygmoCor 8.1) duplicate recordings were measured in 182 people with treated hypertension (aged 61±7 years, 48% male). Agreement between methods was assessed using standard calibration with brachial SBP and DBP (measured with the Xcel device), as well as with brachial mean arterial pressure (MAP; 40% form factor method) and DBP.

RESULTS: The mean difference ± SD for central SBP (cSBP), central DBP (cDBP), and central PP (cPP) between methods were -0.89±3.48mm Hg (intra-class correlation (ICC) 0.977; 95% confidence interval (CI) 0.973-0.982), -0.50±1.54mm Hg (ICC 0.992, 95% CI 0.987-0.993), and -0.42±3.57mm Hg (ICC 0.966, 95% CI 0.958-0.972), indicating good agreement. Wider limits of agreement were observed for central AP (cAP) and central AIx (cAIx) (-0.91±5.31mm Hg; ICC 0.802; 95% CI 0.756-0.839, -0.99±10.91%; ICC 0.749; 95% CI 0.691-0.796). Re-calibration with brachial MAP and DBP resulted in an overestimation of cSBP with Cuff_CBP compared with Ton_CBP (8.58±19.06mm Hg, ICC 0.164, 95% CI -0.029 to 0.321).

CONCLUSION:. cSBP, cDBP, and cPP derived from Cuff_CBP are substantially equivalent to TonCBP, although the level of agreement is dependent on calibration method. Further validity testing of Cuff_CBP by comparison with invasively measured central BP will be required.

Item Type:	Refereed Article
Keywords:	arterial blood pressure, blood pressure, blood pressure determination, diagnostic equipment, hemodynamics, hypertension, oscillometry, pulse wave analysis
Research Division:	Biomedical and Clinical Sciences
Research Group:	Cardiovascular medicine and haematology
Research Field:	Cardiology (incl. cardiovascular diseases)
Objective Division:	Health
Objective Group:	Clinical health
Objective Field:	Clinical health not elsewhere classified
UTAS Author:	Peng, X (Miss Xiaoqing Peng)
UTAS Author:	Schultz, MG (Dr Martin Schultz)
UTAS Author:	Sharman, JE (Professor James Sharman)
ID Code:	109518
Year Published:	2016
Web of Science® Times Cited:	21
Deposited By:	Menzies Institute for Medical Research
Deposited On:	2016-06-21
Last Modified:	2022-08-30
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