Oddy, WH and Hickling, S and Smith, MA and O'Sullivan, TA and Robinson, M and de Klerk, NH and Beilin, LJ and Mori, TA and Syrette, J and Zubrick, SR and Silburn, SR, Dietary intake of omega-3 fatty acids and risk of depressive symptoms in adolescents, Depression and Anxiety, 28, (7) pp. 582-588. ISSN 1091-4269 (2011) [Refereed Article]
OBJECTIVE: In the present investigation, we examined the relationship between dietary n-3 PUFA intake on depression symptomatology in a large prospective pregnancy cohort followed for 17 years.
METHODS: Adolescents enrolled in the Western Australian Pregnancy Cohort (Raine) Study completed a Food Frequency Questionnaire to assess dietary fatty acid intake, as well as other dietary factors at age 14 and a fasting blood sample was taken. Participants also completed the Beck Depression Inventory for Youth (BDI-Y) at age 14 (N = 1,407) and at age 17 (N = 995).
RESULTS: An inverse relationship was observed between intake of both saturated fat and of n-3 PUFA at age 14 and BDI-Y scores at both 14 and 17 years of age. However, after adjusting for energy (kJ) intake and other lifestyle confounders, the relationships were no longer significant.
CONCLUSIONS: Associations previously reported between n3 PUFA and depressive symptoms may be due to collinearity with other dietary and lifestyle factors.
|Item Type:||Refereed Article|
|Keywords:||omega-3 fatty acids, depression, adolescent, Raine Study|
|Research Division:||Medical and Health Sciences|
|Research Group:||Nutrition and Dietetics|
|Research Field:||Clinical and Sports Nutrition|
|Objective Group:||Public Health (excl. Specific Population Health)|
|Author:||Oddy, WH (Professor Wendy Oddy)|
|Web of Science® Times Cited:||23|
|Deposited By:||Menzies Institute for Medical Research|
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