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Associations between aggressive behaviour scores and cardiovascular risk factors in childhood


Louise, S and Warrington, NM and McCaskie, PA and Oddy, WH and Zubrick, SR and Hands, B and Mori, TA and Briollais, L and Silburn, S and Palmer, LJ and Mattes, E and Beilin, LJ, Associations between aggressive behaviour scores and cardiovascular risk factors in childhood, Pediatric Obesity, 7, (4) pp. 319-328. ISSN 2047-6302 (2012) [Refereed Article]

DOI: doi:10.1111/j.2047-6310.2012.00047.x


OBJECTIVE: To examine the influence of aggressive behaviour scores on cardiovascular disease (CVD) risk factors throughout childhood.

METHODS: This study utilized cross-sectional and longitudinal data from the Western Australian Pregnancy Cohort (Raine) Study (n = 2900). Aggressive behaviour scores were derived from the Child Behavior Checklist/4-18(CBCL), Youth Self-Report/11-18 (YSR) and Teacher Report Form/6-18 (TRF). CVD risk factors included body mass index (BMI), blood pressure, fasting lipids and homeostasis model of insulin resistance (HOMA-IR).

RESULTS: Girls with higher aggressive behaviour scores had higher BMI from 10 years of age (P ≤ 0.001), higher BMI trajectories throughout childhood (P = 0.0003) and at 14 years higher HOMA-IR (P = 0.008). At the 14-year survey, this equated to a difference of 1.7 kg/m2 in the predicted BMI between the extreme CBCL scores in girls (top 5% (CBCL ≥ 17) vs. CBCL score = 0). Boys with higher aggressive behaviour scores had higher BMI at 5 years (P = 0.002), lower diastolic pressure at 14 years (P = 0.002) and lower systolic blood pressure trajectories throughout childhood (P = 0.016).

CONCLUSION: Aggressive behaviour influences BMI from early childhood in girls but not boys. If this association is causal, childhood offers the opportunity for early behavioural intervention for obesity prevention.

Item Details

Item Type:Refereed Article
Keywords:Aggression, cardiovascular disease, Raine study, risk factors
Research Division:Biomedical and Clinical Sciences
Research Group:Nutrition and dietetics
Research Field:Nutrition and dietetics not elsewhere classified
Objective Division:Health
Objective Group:Public health (excl. specific population health)
Objective Field:Public health (excl. specific population health) not elsewhere classified
UTAS Author:Oddy, WH (Professor Wendy Oddy)
ID Code:108595
Year Published:2012
Web of Science® Times Cited:8
Deposited By:Menzies Institute for Medical Research
Deposited On:2016-04-26
Last Modified:2017-11-06

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