Louise, S and Warrington, NM and McCaskie, PA and Oddy, WH and Zubrick, SR and Hands, B and Mori, TA and Briollais, L and Silburn, S and Palmer, LJ and Mattes, E and Beilin, LJ, Associations between aggressive behaviour scores and cardiovascular risk factors in childhood, Pediatric Obesity, 7, (4) pp. 319-328. ISSN 2047-6302 (2012) [Refereed Article]
METHODS: This study utilized cross-sectional and longitudinal data from the Western Australian Pregnancy Cohort (Raine) Study (n = 2900). Aggressive behaviour scores were derived from the Child Behavior Checklist/4-18(CBCL), Youth Self-Report/11-18 (YSR) and Teacher Report Form/6-18 (TRF). CVD risk factors included body mass index (BMI), blood pressure, fasting lipids and homeostasis model of insulin resistance (HOMA-IR).
RESULTS: Girls with higher aggressive behaviour scores had higher BMI from 10 years of age (P ≤ 0.001), higher BMI trajectories throughout childhood (P = 0.0003) and at 14 years higher HOMA-IR (P = 0.008). At the 14-year survey, this equated to a difference of 1.7 kg/m2 in the predicted BMI between the extreme CBCL scores in girls (top 5% (CBCL ≥ 17) vs. CBCL score = 0). Boys with higher aggressive behaviour scores had higher BMI at 5 years (P = 0.002), lower diastolic pressure at 14 years (P = 0.002) and lower systolic blood pressure trajectories throughout childhood (P = 0.016).
CONCLUSION: Aggressive behaviour influences BMI from early childhood in girls but not boys. If this association is causal, childhood offers the opportunity for early behavioural intervention for obesity prevention.
|Item Type:||Refereed Article|
|Keywords:||Aggression, cardiovascular disease, Raine study, risk factors|
|Research Division:||Biomedical and Clinical Sciences|
|Research Group:||Nutrition and dietetics|
|Research Field:||Nutrition and dietetics not elsewhere classified|
|Objective Group:||Public health (excl. specific population health)|
|Objective Field:||Public health (excl. specific population health) not elsewhere classified|
|UTAS Author:||Oddy, WH (Professor Wendy Oddy)|
|Web of Science® Times Cited:||8|
|Deposited By:||Menzies Institute for Medical Research|
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